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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605432 Species: Homo sapiens RGD Object: Gene Symbol: RAC1 Name: ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Acc ID: CHEBI:17407 Term: 2-trans,6-trans-farnesyl diphosphate Definition: The trans,trans-stereoisomer of farnesyl diphosphate. CasRN: 372-97-4 Chemical ID: MESH:C004808

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]] farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]]	PMID:18625914