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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tyr
Name: tyrosinase
Acc ID: CHEBI:48131
Term: nonanedioic acid
Definition: An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.
Chemical ID: MESH:C010038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tyrdecreases expressionISOTyr (Mus musculus)6480464CTDazelaic acid results in decreased expression of TYR proteinPMID:20804622
Tyrmultiple interactionsISOTyr (Mus musculus)6480464CTD[Taurine co-treated with azelaic acid] results in decreased activity of TYR protein; [Taurine co-treated with azelaic acid] results in decreased expression of TYR proteinPMID:20804622
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