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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557695
Species: Mus musculus
RGD Object: Gene
Symbol: Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Acc ID: CHEBI:4917
Term: eugenol
Definition: A phenylpropanoid formally derived from guaiacol with an allyl chain substituted para to the hydroxy group. It is a major component of clove essential oil, and exhibits antibacterial, analgesic and antioxidant properties. It has been widely used in dentistry to treat toothache and pulpitis.
Chemical ID: MESH:D005054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv3increases activityEXP 6480464CTDEugenol results in increased activity of TRPV3 proteinPMID:16617338
Trpv3multiple interactionsEXP 6480464CTD[Eugenol results in increased activity of TRPV3 protein] which results in increased transport of CalciumPMID:16617338
Trpv3multiple interactionsISOTRPV3 (Homo sapiens)6480464CTDEugenol binds to and results in increased activity of TRPV3 proteinPMID:21593771
Trpv3multiple interactionsISOTrpv3 (Rattus norvegicus)6480464CTD[Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Eugenol binds to and results in increased activity of TRPV3 proteinPMID:20086034
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