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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553531 Species: Mus musculus RGD Object: Gene Symbol: Rac1 Name: RAS-related C3 botulinum substrate 1

Acc ID: CHEBI:50277 Term: farnesyl diphosphate Definition: A farnesyl phosphate that has formula C15H28O7P2. CasRN: 13058-04-3 Chemical ID: MESH:C004808

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1605432	6480464	CTD	farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]] farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]]	PMID:18625914