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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553030 Species: Mus musculus RGD Object: Gene Symbol: Thbd Name: thrombomodulin

Acc ID: CHEBI:28748 Term: doxorubicin Definition: An anthracycline antibiotic that has formula C27H29NO11. CasRN: 23214-92-8 Chemical ID: MESH:D004317

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1349382	6480464	CTD	Doxorubicin results in increased expression of THBD mRNA Doxorubicin results in increased expression of THBD protein	PMID:17172434
affects expression	EXP		6480464	CTD	Doxorubicin affects the expression of THBD mRNA	PMID:15033991