GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
1352962
Species:
Homo sapiens
RGD Object:
Gene
Symbol:
CYP3A4
Name:
cytochrome P450, family 3, subfamily A, polypeptide 4
Acc ID:
CHEBI:34873
Term:
N-nitrosodiethylamine
Definition:
A nitrosamine that has formula C4H10N2O.
CasRN:
55-18-5
Chemical ID:
MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 protein PMID:11165752 PMID:16246485 multiple interactions ISO RGD:708379 6480464 CTD [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP3A2 mRNA PMID:15885732 multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in decreased expression of CYP3A2 mRNA PMID:16246485 multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP3A2 protein PMID:11165752 multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 protein PMID:16246485 PMID:11165752 multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A2 mRNA PMID:18164116 multiple interactions ISO RGD:708379 6480464 CTD [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP3A2 protein PMID:9744545 
