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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351935 Species: Homo sapiens RGD Object: Gene Symbol: UGT1A7 Name: UDP glucuronosyltransferase 1 family, polypeptide A7

Acc ID: CHEBI:27974 Term: estriol Definition: One of the three main estrogens produced by the human body, having a 3,16alpha,17beta-trihydroxy substitution pattern. CasRN: 50-27-1 Chemical ID: MESH:D004964

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases glucuronidation	EXP		6480464	CTD	UGT1A7 protein results in increased glucuronidation of Estriol UGT1A7 protein results in increased glucuronidation of Estriol analog	PMID:15117964
increases glucuronidation	ISO		6480464	CTD	UGT1A7 protein results in increased glucuronidation of Estriol	PMID:15502008