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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311380
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fanca
Name: FA complementation group A
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fancadecreases expressionISOFanca (Mus musculus)6480464CTDpirinixic acid results in decreased expression of FANCA mRNAPMID:17950772
Fancaincreases expressionISOFanca (Mus musculus)6480464CTDpirinixic acid results in increased expression of FANCA mRNAPMID:20813756 PMID:23811191
Fancamultiple interactionsISOFanca (Mus musculus)6480464CTD[pirinixic acid co-treated with PPARA] results in increased expression of FANCA mRNA; NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of FANCA mRNA]; PPARA protein promotes the reaction [pirinixic acid results in decreased expression of FANCA mRNA]PMID:17950772 PMID:20813756
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