GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt1 | multiple interactions | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of SIRT1 protein]; Erythropoietin results in increased expression of and results in increased activity of SIRT1 protein; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]] | PMID:28456571 | | ||||||||||||||||||||||
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