GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt1 | increases activity | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | myricetin results in increased activity of SIRT1 protein | PMID:22245592 | Sirt1 | increases expression | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | myricetin results in increased expression of SIRT1 protein | PMID:22245592 | Sirt1 | multiple interactions | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein; [myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein | PMID:22245592 | | ||||||||||||||||||||||
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