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GENE - TERM ANNOTATION REPORT

RGD ID: 1308053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Poll
Name: DNA polymerase lambda
Acc ID: GO:0006303
Term: double-strand break repair via nonhomologous end joining
Definition: The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
Definition Source(s): GOC:rph, PMID:10827453, PMID:24837021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pollinvolved_inISOPOLL (Homo sapiens)1624291RGD PMID:19806195 PMID:30250067

PMID:19806195 PMID:30250067
Pollinvolved_inIBAPANTHER:PTN000138687 or PomBase:SPAC2F7.06c or SGD:S000000607 or TAIR:locus:2194610 or UniProtKB:Q9UGP51600115GO_CentralGO_REF:0000033

GO_REF:0000033
Pollinvolved_inISSUniProtKB:Q9UGP51600115UniProtGO_REF:0000024

GO_REF:0000024
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