GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcr | decreases phosphorylation | ISO | BCR (Homo sapiens) | 6480464 | CTD | nilotinib results in decreased phosphorylation of BCR protein mutant form | PMID:19878872 | Bcr | multiple interactions | ISO | BCR (Homo sapiens) | 6480464 | CTD | nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]; nilotinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA] | PMID:16849647 | | ||||||||||||||||||||||
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