GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcr | decreases expression | ISO | BCR (Homo sapiens) | 6480464 | CTD | vorinostat results in decreased expression of BCR mRNA mutant form; vorinostat results in decreased expression of BCR protein mutant form | PMID:12446442 | Bcr | multiple interactions | ISO | BCR (Homo sapiens) | 6480464 | CTD | [Dasatinib co-treated with Vorinostat] results in decreased expression of BCR protein mutant form; [Dasatinib co-treated with Vorinostat] results in decreased phosphorylation of BCR protein mutant form; [tozasertib co-treated with Vorinostat] results in decreased activity of BCR protein mutant form; [Vorinostat co-treated with Imatinib Mesylate] results in decreased expression of BCR protein mutant form; [Vorinostat co-treated with Imatinib Mesylate] results in decreased phosphorylation of BCR protein mutant form | PMID:12446442 PMID:17020995 PMID:18829489 | | ||||||||||||||||||||||
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