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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp1
Name: matrix metallopeptidase 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp1multiple interactionsEXP 6480464CTD[sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA; SERPINH1 protein promotes the reaction [[sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA]PMID:35963424
Mmp1affects expressionISOMMP1 (Homo sapiens)6480464CTDsodium arsenite affects the expression of MMP1 mRNAPMID:34032870
Mmp1decreases expressionISOMMP1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of MMP1 mRNAPMID:12377979 PMID:30191986
Mmp1increases expressionISOMMP1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of MMP1 mRNA; sodium arsenite results in increased expression of MMP1 proteinPMID:22714537 PMID:23876855 PMID:28595984 PMID:30090515 PMID:31120745 PMID:36089002
Mmp1multiple interactionsISOMMP1 (Homo sapiens)6480464CTDATF2 protein promotes the reaction [sodium arsenite results in increased expression of MMP1 mRNA]PMID:30090515
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