GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp1 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA | PMID:34747641 | Mmp1 | increases expression | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of MMP1; Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA; Tetrachlorodibenzodioxin results in increased expression of MMP1 protein | PMID:12377990 PMID:15075337 PMID:15531779 PMID:15982688 PMID:17003102 PMID:18061397 PMID:19755661 PMID:20106945 PMID:21632981 PMID:23152189 PMID:23625689 PMID:24469321 | Mmp1 | multiple interactions | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of MMP1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; AHR protein promotes the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; KN 62 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 protein]; MMP1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of MMP2 protein]; MMP1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of MMP1 protein]; SB 203580 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of MMP1 protein]; Tetrachlorodibenzodioxin promotes the reaction [ATF2 protein binds to MMP1 promoter]; Tetrachlorodibenzodioxin promotes the reaction [FOS protein binds to MMP1 promoter]; Tetrachlorodibenzodioxin promotes the reaction [JUN protein binds to MMP1 promoter]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of MMP1 protein; Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA] | PMID:15075337 PMID:15982688 PMID:23625689 PMID:24469321 | | ||||||||||||||||||||||
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