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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307364
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Spata13
Name: spermatogenesis associated 13
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spata13affects expressionEXP 6480464CTDEstradiol affects the expression of SPATA13 mRNAPMID:32145629
Spata13increases expressionISOSPATA13 (Homo sapiens)6480464CTDEstradiol results in increased expression of SPATA13 mRNAPMID:17962382 PMID:23019147 PMID:31614463
Spata13multiple interactionsISOSPATA13 (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of SPATA13 mRNA; ESR1 protein affects the reaction [Estradiol promotes the reaction [NCOA3 protein binds to SPATA13 gene]]; Estradiol promotes the reaction [ESR1 protein binds to SPATA13 gene]PMID:17962382 PMID:30165855
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