GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Map2k4 | increases expression | EXP | | 6480464 | CTD | Quercetin results in increased expression of MAP2K4 mRNA | PMID:17103110 | Map2k4 | decreases expression | ISO | MAP2K4 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of MAP2K4 mRNA | PMID:15309432 | Map2k4 | increases expression | ISO | MAP2K4 (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of MAP2K4 mRNA | PMID:23727915 | Map2k4 | multiple interactions | ISO | MAP2K4 (Homo sapiens) | 6480464 | CTD | [Cisplatin co-treated with Quercetin] results in increased expression of MAP2K4 mRNA; Quercetin inhibits the reaction [[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein] | PMID:16963249 PMID:27514524 | |
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