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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdm2
Name: MDM2 proto-oncogene
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2multiple interactionsISOMDM2 (Homo sapiens)6480464CTDwortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein]; wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]PMID:17935137
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