GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mdm2 | increases expression | EXP | | 6480464 | CTD | pirinixic acid results in increased expression of MDM2 mRNA | PMID:15890375 PMID:19162173 | Mdm2 | multiple interactions | EXP | | 6480464 | CTD | MDM2 protein affects the reaction [pirinixic acid results in increased activity of PPARA protein]; MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ACOX1 mRNA]; MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ANGPTL4 mRNA]; MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of CYP4A1 mRNA]; MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of EHHADH mRNA]; MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of FABP1 mRNA]; MDM2 protein promotes the reaction [pirinixic acid results in increased expression of PPARA protein]; pirinixic acid promotes the reaction [[PPARA protein binds to MDM2 protein] which binds to ACOX1 promoter]; pirinixic acid promotes the reaction [[PPARA protein binds to MDM2 protein] which binds to DBI promoter]; pirinixic acid promotes the reaction [MDM2 protein binds to PPARA protein] | PMID:19103650 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |