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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdm2
Name: MDM2 proto-oncogene
Acc ID: CHEBI:18291
Term: manganese atom
Definition: A manganese group element atom that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2decreases expressionEXP 6480464CTDManganese results in decreased expression of MDM2 proteinPMID:25791630
Mdm2multiple interactionsEXP 6480464CTD[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein; PPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein]PMID:25791630
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