GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dek | increases expression | ISO | DEK (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of DEK mRNA; Estradiol results in increased expression of DEK protein | PMID:23071688 | Dek | increases response to substance | ISO | DEK (Homo sapiens) | 6480464 | CTD | DEK protein results in increased susceptibility to Estradiol | PMID:23071688 | Dek | multiple interactions | ISO | DEK (Homo sapiens) | 6480464 | CTD | 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol results in increased expression of DEK protein]; Estradiol promotes the reaction [ESR1 protein binds to DEK promoter]; Estradiol promotes the reaction [MYC protein binds to DEK promoter]; fulvestrant inhibits the reaction [Estradiol results in increased expression of DEK protein] | PMID:23071688 | | ||||||||||||||||||||||
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