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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303075
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90ab1
Name: heat shock protein 90 alpha family class B member 1
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90ab1decreases expressionEXP 6480464CTDQuercetin results in decreased expression of HSP90AB1 mRNA; Quercetin results in decreased expression of HSP90AB1 proteinPMID:11318950 PMID:17103110 PMID:18095365
Hsp90ab1decreases expressionISOHSP90AB1 (Homo sapiens)6480464CTDQuercetin results in decreased expression of HSP90AB1 proteinPMID:19207037
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