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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10940 Species: Mus musculus RGD Object: Gene Symbol: Myc Name: myelocytomatosis oncogene

Acc ID: CHEBI:2038 Term: 5-azacytidine Definition: A N-glycosyl-1,3,5-triazine that has formula C8H12N4O5. CasRN: 320-67-2 Chemical ID: MESH:D001374

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:731438	6480464	CTD	Azacitidine analog results in decreased expression of MYC mRNA	PMID:18045574
multiple interactions	ISO	RGD:731438	6480464	CTD	MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein] MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]	PMID:19451745