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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10828 Species: Mus musculus RGD Object: Gene Symbol: Jun Name: Jun oncogene

Acc ID: CHEBI:28527 Term: rutin Definition: A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups. CasRN: 153-18-4 Chemical ID: MESH:D012431

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:734356	6480464	CTD	Rutin results in decreased expression of JUN protein	PMID:20015448
multiple interactions	ISO	RGD:734356	6480464	CTD	Rutin results in increased susceptibility to [Vitamin E results in decreased expression of JUN protein] Vitamin E results in increased susceptibility to [Rutin results in decreased expression of JUN protein]	PMID:20015448