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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10698
Species: Mus musculus
RGD Object: Gene
Symbol: Gstm2
Name: glutathione S-transferase, mu 2
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstm2affects metabolic processingEXP 6480464CTDGSTM5 protein affects the metabolism of GlutathionePMID:9545290
Gstm2affects metabolic processingISOGstm2 (Rattus norvegicus)6480464CTDGSTM2 protein affects the metabolism of GlutathionePMID:8924604
Gstm2affects metabolic processingISOGSTM2 (Homo sapiens)6480464CTDGSTM2 protein affects the metabolism of GlutathionePMID:10858281
Gstm2multiple interactionsISOGstm2 (Rattus norvegicus)6480464CTDDinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione]; GSTM2 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]; GSTM2 protein affects the metabolism of [styrene oxide co-treated with Glutathione]PMID:2604743 PMID:8973562 PMID:9794801
Gstm2multiple interactionsISOGSTM2 (Homo sapiens)6480464CTD[GSTM2 protein co-treated with Glutathione] results in increased metabolism of amodiaquine quinoneimine; [GSTM2 protein co-treated with Glutathione] results in increased metabolism of desethylamodiaquinePMID:28478157
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