Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10551
Species: Mus musculus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1 (alpha)
Acc ID: CHEBI:8107
Term: phenytoin
Definition: A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
Chemical ID: MESH:D010672
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1increases expressionEXP 6480464CTDPhenytoin results in increased expression of ESR1 mRNA; Phenytoin results in increased expression of ESR1 proteinPMID:19490052
Go Back to source page   Continue to Ontology report