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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10310
Species: Mus musculus
RGD Object: Gene
Symbol: Cd44
Name: CD44 antigen
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd44decreases expressionISOCD44 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of CD44 mRNA; Arsenic Trioxide results in decreased expression of CD44 mRNA alternative form; Arsenic Trioxide results in decreased expression of CD44 protein; Arsenic Trioxide results in decreased expression of CD44 protein alternative formPMID:15553829 PMID:19804631 PMID:22391160 PMID:23098472
Cd44multiple interactionsISOCD44 (Homo sapiens)6480464CTD[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD44 mRNAPMID:15894607
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