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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10274 Species: Mus musculus RGD Object: Gene Symbol: Calca Name: calcitonin/calcitonin-related polypeptide, alpha

Acc ID: CHEBI:9948 Term: verapamil Definition: An L-type calcium channel blocker of the phenylalkylamine class. CasRN: 52-53-9 Chemical ID: MESH:D014700

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:730992	6480464	CTD	Verapamil inhibits the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] Verapamil inhibits the reaction [[Ionomycin co-treated with Lipopolysaccharides] results in increased expression of CALCA protein]	PMID:20682585