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GENE - TERM ANNOTATION REPORT

5 Annotations Found.

An association has been curated linking Pcsk1 and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ohagi S, etal., Diabetes. 1996 Jul;45(7):897-901.
  • The annotation has been inferred from sequence orthology with PCSK1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Ohagi S, etal., Diabetes. 1996 Jul;45(7):897-901.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 61 papers in RGD have been used to annotate Pcsk1
  • Qualifier: no_association
  • Curation Notes: DNA:missense mutations:cds:p.R53Q, p.Q638E (human)


    • An association has been curated linking Pcsk1 and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Patriti A, etal., Surgery. 2007 Jul;142(1):74-85.
  • 2 additional annotations were made from Patriti A, etal., Surgery. 2007 Jul;142(1):74-85.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 61 papers in RGD have been used to annotate Pcsk1


    • An association has been curated linking Pcsk1 and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Guest PC, etal., J Endocrinol. 2002 Dec;175(3):637-47.
  • 4 additional annotations were made from Guest PC, etal., J Endocrinol. 2002 Dec;175(3):637-47.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 61 papers in RGD have been used to annotate Pcsk1
  • Curation Notes: protein:altered expression:pancreatic islet (rat)


    • An association has been curated linking Pcsk1 and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Lu H, etal., Mol Cell Proteomics. 2008 Aug;7(8):1434-51. Epub 2008 Apr 30.
  • The annotation has been inferred from sequence orthology with Pcsk1 (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Lu H, etal., Mol Cell Proteomics. 2008 Aug;7(8):1434-51. Epub 2008 Apr 30.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 61 papers in RGD have been used to annotate Pcsk1
  • Curation Notes: protein:decreased expression:pancreatic islet (mouse)


    • An association has been curated linking Pcsk1 and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Wideman RD, etal., Mol Ther. 2009 Jan;17(1):191-8. Epub 2008 Oct 21.
  • The annotation has been inferred from sequence orthology with Pcsk1 (Mus musculus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Wideman RD, etal., Mol Ther. 2009 Jan;17(1):191-8. Epub 2008 Oct 21.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 61 papers in RGD have been used to annotate Pcsk1
  • Curation Notes: protein:increased expression:pancreatic alpha cell (mouse)


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