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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Lep and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Han HR, etal., Clin Genet. 2008 Aug;74(2):105-15. Epub 2008 Jun 28.
  • The annotation has been inferred from sequence orthology with LEP (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 6 additional annotations were made from Han HR, etal., Clin Genet. 2008 Aug;74(2):105-15. Epub 2008 Jun 28.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 141 papers in RGD have been used to annotate Lep
  • Qualifier: susceptibility
  • Curation Notes: DNA:SNP,haplotype:promoter,3'utr: -632G>A, +4998A>C (human)


    • An association has been curated linking Lep and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Chen WS, etal., Mol Cell Biol. 2009 Jun;29(11):3151-62. Epub 2009 Mar 16.
  • 8 additional annotations were made from Chen WS, etal., Mol Cell Biol. 2009 Jun;29(11):3151-62. Epub 2009 Mar 16.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 141 papers in RGD have been used to annotate Lep


    • An association has been curated linking Lep and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with LEP (Homo sapiens) [(EXP) inferred from experiment]
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: CTD Direct Evidence: therapeutic
  • Original References(s): PMID:15070752


    • An association has been curated linking Lep and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Lep (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036


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