Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

9 Annotations Found.

An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Falini B, etal., N Engl J Med. 2005 Jan 20;352(3):254-66.
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Falini B, etal., N Engl J Med. 2005 Jan 20;352(3):254-66.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Grisendi S and Pandolfi PP, N Engl J Med. 2005 Jan 20;352(3):291-2.
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(TAS) traceable author statement]
  • 29 additional annotations were made from Grisendi S and Pandolfi PP, N Engl J Med. 2005 Jan 20;352(3):291-2.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Rau R, etal., Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29.
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 5 additional annotations were made from Rau R, etal., Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Gale RE, etal., Blood. 2008 Mar 1;111(5):2776-84. Epub 2007 Oct 23.
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Gale RE, etal., Blood. 2008 Mar 1;111(5):2776-84. Epub 2007 Oct 23.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1
  • Qualifier: disease_progression
  • Curation Notes: DNA:mutation:exon:


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from OMIM Disease Annotation Pipeline
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Kuzelova K, etal., PLoS One. 2015 May 20;10(5):e0127637. doi: 10.1371/journal.pone.0127637. eCollection 2015.
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Kuzelova K, etal., PLoS One. 2015 May 20;10(5):e0127637. doi: 10.1371/journal.pone.0127637. eCollection 2015.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1
  • Qualifier: disease_progression


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Vassiliou GS, etal., Nat Genet. 2011 May;43(5):470-5. doi: 10.1038/ng.796. Epub 2011 Mar 27.
  • The annotation has been inferred from sequence orthology with Npm1 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Vassiliou GS, etal., Nat Genet. 2011 May;43(5):470-5. doi: 10.1038/ng.796. Epub 2011 Mar 27.
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1
  • Qualifier: onset


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(EXP) inferred from experiment]
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:19822134 PMID:21441929 PMID:23877794 PMID:27992414 PMID:30420649


    • An association has been curated linking Npm1 and acute myeloid leukemia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with NPM1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 344 RGD objects have been annotated to acute myeloid leukemia  (DOID:9119)
  • 34 papers in RGD have been used to annotate Npm1
  • Curation Notes: ClinVar Annotator: match by term: Acute myeloid leukemia | ClinVar Annotator: match by term: Acute myeloid leukemia, adult
  • Original References(s): PMID:15659725 PMID:19657110 PMID:20026798 PMID:25741868 PMID:28492532 PMID:32581362


    • Go Back to source page   Continue to Ontology report