Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Murugan P, etal., J Biosci. 2008 Mar;33(1):63-72.
  • 2 additional annotations were made from Murugan P, etal., J Biosci. 2008 Mar;33(1):63-72.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: protein:decreased expression:erythrocyte (rat)


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Tiwari S, etal., J Am Soc Nephrol. 2007 Oct;18(10):2661-71. Epub 2007 Sep 12.
  • 5 additional annotations were made from Tiwari S, etal., J Am Soc Nephrol. 2007 Oct;18(10):2661-71. Epub 2007 Sep 12.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: protein:decreased expression:kidney


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Calle C, etal., BMC Mol Biol. 2008 Jul 18;9:65.
  • 3 additional annotations were made from Calle C, etal., BMC Mol Biol. 2008 Jul 18;9:65.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: mRNA, protein:increased expression:liver, adipose tissue (rat)


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Blondel O, etal., Am J Physiol. 1990 Mar;258(3 Pt 1):E459-67. doi: 10.1152/ajpendo.1990.258.3.E459.
  • 6 additional annotations were made from Blondel O, etal., Am J Physiol. 1990 Mar;258(3 Pt 1):E459-67. doi: 10.1152/ajpendo.1990.258.3.E459.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: protein:altered activity:liver plasma membrane


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Kim MH, etal., PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.
  • The annotation has been inferred from sequence orthology with INSR (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Kim MH, etal., PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Qualifier: treatment


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with INSR (Homo sapiens) [(EXP) inferred from experiment]
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:9243097 PMID:22138235


    • An association has been curated linking Insr and Experimental Diabetes Mellitus in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Tozzo E and Desbuquois B, Diabetes. 1992 Dec;41(12):1609-16. doi: 10.2337/diab.41.12.1609.
  • 10 additional annotations were made from Tozzo E and Desbuquois B, Diabetes. 1992 Dec;41(12):1609-16. doi: 10.2337/diab.41.12.1609.
  • 610 RGD objects have been annotated to Experimental Diabetes Mellitus  (DOID:9005643)
  • 115 papers in RGD have been used to annotate Insr
  • Qualifier: disease_progression
  • Curation Notes: mRNA:increased expression:liver nuclei, liver cell membrane (rat)


    • Go Back to source page   Continue to Ontology report