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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Park BL, etal., J Hum Genet. 2009 Dec;54(12):709-12. doi: 10.1038/jhg.2009.102. Epub 2009 Oct 30.
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Park BL, etal., J Hum Genet. 2009 Dec;54(12):709-12. doi: 10.1038/jhg.2009.102. Epub 2009 Oct 30.
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Qualifier: susceptibility
  • Curation Notes: DNA:missense mutation:cds: (rs6267) (human)


    • An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Shifman S, etal., Am J Hum Genet 2002 Dec;71(6):1296-302. Epub 2002 Oct 25.
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Shifman S, etal., Am J Hum Genet 2002 Dec;71(6):1296-302. Epub 2002 Oct 25.
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Curation Notes: DNA:SNPs, haplotype


    • An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Lindenmayer JP, etal., Schizophr Res. 2015 Oct;168(1-2):279-84. doi: 10.1016/j.schres.2015.07.037. Epub 2015 Aug 6.
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Lindenmayer JP, etal., Schizophr Res. 2015 Oct;168(1-2):279-84. doi: 10.1016/j.schres.2015.07.037. Epub 2015 Aug 6.
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Qualifier: treatment
  • Curation Notes: DNA:polymorphism:cds:rs4680(p.V158M)(human)


    • An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(EXP) inferred from experiment]
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:16234811 PMID:17123785 PMID:18583979 PMID:20561508


    • An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Abdolmaleky HM, etal., Hum Mol Genet. 2006 Nov 1;15(21):3132-45. doi: 10.1093/hmg/ddl253. Epub 2006 Sep 19.
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(IDA) inferred from direct assay]
  • 8 additional annotations were made from Abdolmaleky HM, etal., Hum Mol Genet. 2006 Nov 1;15(21):3132-45. doi: 10.1093/hmg/ddl253. Epub 2006 Sep 19.
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Curation Notes: DNA:promoter:Hypomethylation


    • An association has been curated linking Comt and schizophrenia in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with COMT (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 1112 RGD objects have been annotated to schizophrenia  (DOID:5419)
  • 135 papers in RGD have been used to annotate Comt
  • Curation Notes: ClinVar Annotator: match by term: Schizophrenia | ClinVar Annotator: match by term: Schizophrenia, susceptibility to
  • Original References(s): PMID:10395222 PMID:10459407 PMID:11171904 PMID:11381111 PMID:11502905 PMID:11772685 PMID:11925305 PMID:12192614 PMID:12359690 PMID:12402217 PMID:12436243 PMID:12595695 PMID:12611827 PMID:12716966 PMID:12842306 PMID:14966473 PMID:15169701 PMID:15457404 PMID:15457497 PMID:15645182 PMID:15652872 PMID:15821730 PMID:15824744 PMID:15935994 PMID:16043133 PMID:16130008 PMID:16135635 PMID:16275815 PMID:16513880 PMID:16542388 PMID:17504906 PMID:21280081 PMID:21681106 PMID:25741868 PMID:30208311 PMID:7304673 PMID:7585135 PMID:8807664 PMID:8886163 PMID:8941353 PMID:9110364


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