MITOGEN ACTIVATED PROTEIN KINASE SIGNALING PATHWAY (PW:0000007)

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Description

The mitogen activated protein kinase pathways (MAPKs) represent highly conserved cascades activated in response to effectors downstream of receptor tyrosine kinases (RTKs) or in some cases G-protein coupled receptors (GPCRs), and in response to inflammatory cytokines and stress. Together, they control many cellular processes. The hallmark of MAPK pathways is the shared architecture of a three-tier signaling core: MAP3K/MAP2K/MAPK. The downstream tier and main effectors MAPKs are activated by pho

Pathway Diagram:

Ariadne Genomics Inc. Erk5 MAPK signaling pathway p38 MAPK signaling pathway c-Jun N-terminal kinases MAPK signaling pathway The extracellular signal-regulated RAF/MEK/ERK pathway immune response motility apoptosis proliferation differentiation survival cytokine receptors RTK Rho Ras Traf effectors2 adapters effectors1 inflammatory cytokines GF stress conditions
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mitogen activated protein kinase signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6907045
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:6907045
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:6907045
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:6907045
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:6907045
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:6907045
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:6907045
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6907045
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:6907045
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:6907045
G Cacna1b calcium voltage-gated channel subunit alpha1 B JBrowse link 3 1,740,026 1,924,959 RGD:6907045
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:6907045
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:6907045
G Cacna1e calcium voltage-gated channel subunit alpha1 E JBrowse link 13 71,899,445 72,534,992 RGD:6907045
G Cacna1f calcium voltage-gated channel subunit alpha1 F JBrowse link X 15,712,709 15,741,135 RGD:6907045
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:6907045
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:6907045
G Cacna1i calcium voltage-gated channel subunit alpha1 I JBrowse link 7 121,521,787 121,619,300 RGD:6907045
G Cacna1s calcium voltage-gated channel subunit alpha1 S JBrowse link 13 52,889,570 52,964,558 RGD:6907045
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:6907045
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 JBrowse link 8 116,154,661 116,285,643 RGD:6907045
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 JBrowse link 16 4,871,348 5,795,825 RGD:6907045
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 JBrowse link 4 151,298,548 151,409,263 RGD:6907045
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 JBrowse link 10 85,954,138 85,974,764 RGD:6907045
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:6907045
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:6907045
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:6907045
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 JBrowse link 10 95,921,479 95,934,170 RGD:6907045
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 JBrowse link 7 119,228,112 119,353,332 RGD:6907045
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 JBrowse link 1 192,613,766 192,708,371 RGD:6907045
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:6907045
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 JBrowse link 10 96,122,240 96,166,606 RGD:6907045
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 JBrowse link 1 64,307,684 64,322,124 RGD:6907045
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 JBrowse link 1 64,374,547 64,405,380 RGD:6907045
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:6907045
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6907045
G Ccdc88b coiled-coil domain containing 88B JBrowse link 1 222,102,436 222,118,485 RGD:6907045
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6907045
G Cdc25b cell division cycle 25B JBrowse link 3 123,731,539 123,741,696 RGD:6907045
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:6907045
G Chp1 calcineurin-like EF-hand protein 1 JBrowse link 3 111,354,506 111,389,998 RGD:6907045
G Chp2 calcineurin-like EF hand protein 2 JBrowse link 1 192,169,634 192,173,228 RGD:6907045
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 1 263,848,829 263,884,354 RGD:6907045
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:6907045
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:6907045
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:6907045
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6907045
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:6907045
G Dusp10 dual specificity phosphatase 10 JBrowse link 13 104,284,660 104,321,455 RGD:6907045
G Dusp14 dual specificity phosphatase 14 JBrowse link 10 71,363,688 71,383,602 RGD:6907045
G Dusp16 dual specificity phosphatase 16 JBrowse link 4 168,470,141 168,551,346 RGD:6907045
G Dusp2 dual specificity phosphatase 2 JBrowse link 3 119,776,925 119,779,110 RGD:6907045
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:6907045
G Dusp3 dual specificity phosphatase 3 JBrowse link 10 89,904,578 89,918,296 RGD:6907045
G Dusp4 dual specificity phosphatase 4 JBrowse link 16 61,080,767 61,090,973 RGD:6907045
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:6907045
G Dusp6 dual specificity phosphatase 6 JBrowse link 7 41,475,163 41,479,393 RGD:6907045
G Dusp7 dual specificity phosphatase 7 JBrowse link 8 115,069,095 115,076,130 RGD:6907045
G Dusp8 dual specificity phosphatase 8 JBrowse link 1 215,030,429 215,043,111 RGD:6907045
G Dusp9 dual specificity phosphatase 9 JBrowse link X 157,168,143 157,172,068 RGD:6907045
G Ecsit ECSIT signalling integrator JBrowse link 8 23,085,598 23,099,064 RGD:6907045
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6907045
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6907045
G Elk1 ELK1, ETS transcription factor JBrowse link X 1,287,875 1,304,822 RGD:6907045
G Elk4 ELK4, ETS transcription factor JBrowse link 13 48,788,262 48,813,267 RGD:6907045
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1582137
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6907045
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6907045
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:6907045
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:6907045
G Fgf11 fibroblast growth factor 11 JBrowse link 10 56,403,320 56,410,816 RGD:6907045
G Fgf12 fibroblast growth factor 12 JBrowse link 11 75,606,360 76,171,078 RGD:6907045
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:6907045
G Fgf14 fibroblast growth factor 14 JBrowse link 15 110,382,274 111,077,027 RGD:6907045
G Fgf16 fibroblast growth factor 16 JBrowse link X 76,786,728 76,796,311 RGD:6907045
G Fgf17 fibroblast growth factor 17 JBrowse link 15 52,326,758 52,337,360 RGD:6907045
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:6907045
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:6907045
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6907045
G Fgf20 fibroblast growth factor 20 JBrowse link 16 55,152,748 55,159,352 RGD:6907045
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:6907045
G Fgf22 fibroblast growth factor 22 JBrowse link 7 12,829,785 12,831,675 RGD:6907045
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:6907045
G Fgf3 fibroblast growth factor 3 JBrowse link 1 218,003,018 218,006,942 RGD:6907045
G Fgf4 fibroblast growth factor 4 JBrowse link 1 218,024,537 218,029,539 RGD:6907045
G Fgf5 fibroblast growth factor 5 JBrowse link 14 12,974,921 12,996,046 RGD:6907045
G Fgf6 fibroblast growth factor 6 JBrowse link 4 159,563,798 159,572,333 RGD:6907045
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:6907045
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:6907045
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:6907045
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:6907045
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:6907045
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:6907045
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:6907045
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:6907045
G Flnb filamin B JBrowse link 15 18,750,152 18,883,019 RGD:6907045
G Flnc filamin C JBrowse link 4 56,710,934 56,738,779 RGD:6907045
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6907045
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6907045
G Gadd45b growth arrest and DNA-damage-inducible, beta JBrowse link 7 11,646,283 11,648,338 RGD:6907045
G Gadd45g growth arrest and DNA-damage-inducible, gamma JBrowse link 17 13,391,474 13,393,219 RGD:6907045
G Gna12 G protein subunit alpha 12 JBrowse link 12 15,890,202 15,971,212 RGD:6907045
G Gng12 G protein subunit gamma 12 JBrowse link 4 97,634,925 97,763,478 RGD:6907045
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:6907045
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6907045
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6907045
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:6907045
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:6907045
G Hspa2 heat shock protein family A member 2 JBrowse link 6 99,433,575 99,436,288 RGD:6907045
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6907045
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6907045
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6907045
G Ikbkg inhibitor of nuclear factor kappa B kinase subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6907045
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6907045
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6907045
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:6907045
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:6907045
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6907045
G Jund JunD proto-oncogene, AP-1 transcription factor subunit JBrowse link 16 20,485,028 20,486,707 RGD:6907045
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:6907045
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:6907045
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:6907045
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6907045
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:6907045
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:6907045
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6907045
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:6907045
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6907045
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 1 221,043,119 221,056,420 RGD:6907045
G Map3k12 mitogen activated protein kinase kinase kinase 12 JBrowse link 7 144,102,275 144,120,306 RGD:6907045
G Map3k13 mitogen-activated protein kinase kinase kinase 13 JBrowse link 11 82,744,391 82,938,357 RGD:6907045
G Map3k14 mitogen-activated protein kinase kinase kinase 14 JBrowse link 10 91,303,428 91,353,601 RGD:6907045
G Map3k2 mitogen activated protein kinase kinase kinase 2 JBrowse link 18 24,961,250 25,025,488 RGD:6907045
G Map3k20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 3 58,965,025 59,120,507 RGD:6907045
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:6907045
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:6907045
G Map3k6 mitogen-activated protein kinase kinase kinase 6 JBrowse link 5 151,435,679 151,448,329 RGD:6907045
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6907045
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 17 56,109,403 56,129,925 RGD:6907045
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 JBrowse link 1 87,937,126 87,959,514 RGD:6907045
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 JBrowse link 1 221,710,622 221,726,274 RGD:6907045
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 JBrowse link 6 3,276,732 3,444,519 RGD:6907045
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 JBrowse link 9 46,657,444 46,782,545 RGD:6907045
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6907045
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6907045
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6907045
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6907045
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:6907045
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6907045
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6907045
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:6907045
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6907045
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 3 81,295,023 81,304,181 RGD:6907045
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:6907045
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 10 14,259,394 14,299,276 RGD:6907045
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6907045
G Mapkapk2 mitogen-activated protein kinase-activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:6907045
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:6907045
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:6907045
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6907045
G Max MYC associated factor X JBrowse link 6 99,984,260 100,011,460 RGD:6907045
G Mecom MDS1 and EVI1 complex locus JBrowse link 2 117,396,084 117,993,604 RGD:6907045
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:6907045
G Mknk1 MAP kinase-interacting serine/threonine kinase 1 JBrowse link 5 134,691,852 134,730,887 RGD:6907045
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 JBrowse link 7 11,908,107 11,919,161 RGD:6907045
G Mos Moloney sarcoma oncogene JBrowse link 5 16,746,085 16,747,392 RGD:6907045
G Mras muscle RAS oncogene homolog JBrowse link 8 107,629,028 107,656,851 RGD:6907045
G Myc myelocytomatosis oncogene JBrowse link 7 102,586,313 102,591,240 RGD:6907045
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:6907045
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:6907045
G Nfatc4 nuclear factor of activated T-cells 4 JBrowse link 15 34,493,163 34,502,238 RGD:6907045
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6907045
G Nfkb2 nuclear factor kappa B subunit 2 JBrowse link 1 266,050,634 266,059,277 RGD:6907045
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6907045
G Nlk nemo like kinase JBrowse link 10 65,840,052 65,963,932 RGD:6907045
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6907045
G Nras neuroblastoma RAS viral oncogene homolog JBrowse link 2 205,553,119 205,563,716 RGD:6907045
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:6907045
G Ntf4 neurotrophin 4 JBrowse link 1 101,405,314 101,408,145 RGD:6907045
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:6907045
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6907045
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:70317
RGD:6907045
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:6907045
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:6907045
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:6907045
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:6907045
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:6907045
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:6907045
G Pla2g12a phospholipase A2, group XIIA JBrowse link 2 235,311,664 235,327,972 RGD:6907045
G Pla2g12b phospholipase A2, group XIIB JBrowse link 20 28,989,440 29,007,967 RGD:6907045
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:6907045
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:6907045
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:6907045
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:6907045
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:6907045
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:6907045
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6907045
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:6907045
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:6907045
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:6907045
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:6907045
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6907045
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A JBrowse link 6 94,433,658 94,484,979 RGD:6907045
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B JBrowse link 6 8,219,385 8,280,127 RGD:6907045
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:6907045
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:6907045
G Ppp3cc protein phosphatase 3 catalytic subunit gamma JBrowse link 15 51,896,427 51,968,075 RGD:6907045
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:6907045
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta JBrowse link 5 64,945,583 64,946,578 RGD:6907045
G Ppp5c protein phosphatase 5, catalytic subunit JBrowse link 1 78,944,054 78,968,361 RGD:6907045
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:6907045
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:6907045
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:6907045
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:6907045
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:6907045
G Prkx protein kinase, X-linked JBrowse link X 45,080,963 45,125,095 RGD:6907045
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 JBrowse link 1 103,197,918 103,258,309 RGD:6907045
G Ptpn7 protein tyrosine phosphatase, non-receptor type 7 JBrowse link 13 51,958,023 51,971,431 RGD:6907045
G Ptprr protein tyrosine phosphatase, receptor type, R JBrowse link 7 59,039,717 59,325,925 RGD:6907045
G Rac1 ras-related C3 botulinum toxin substrate 1 JBrowse link 12 13,090,316 13,111,841 RGD:6907045
G Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) JBrowse link 7 119,769,708 119,797,111 RGD:6907045
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:6907045
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:6907045
G Rap1b RAP1B, member of RAS oncogene family JBrowse link 7 60,850,406 60,878,226 RGD:6907045
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:6907045
G Rasa1 RAS p21 protein activator 1 JBrowse link 2 13,617,021 13,696,531 RGD:6907045
G Rasa2 RAS p21 protein activator 2 JBrowse link 8 104,417,827 104,542,313 RGD:6907045
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:6907045
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:6907045
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:6907045
G Rasgrp2 RAS guanyl releasing protein 2 JBrowse link 1 221,771,238 221,788,765 RGD:6907045
G Rasgrp3 RAS guanyl releasing protein 3 JBrowse link 6 21,072,634 21,171,619 RGD:6907045
G Rasgrp4 RAS guanyl releasing protein 4 JBrowse link 1 88,078,350 88,094,331 RGD:6907045
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6907045
G RGD1564956 similar to calcium binding protein P22 JBrowse link 5 70,747,534 70,749,967 RGD:6907045
G RGD1565395 similar to stathmin 1/oncoprotein 18) JBrowse link 10 83,147,416 83,147,903 RGD:6907045
G RGD1565588 similar to calcium binding protein P22 JBrowse link 4 6,477,461 6,479,158 RGD:6907045
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:6907045
G Rps6ka2 ribosomal protein S6 kinase A2 JBrowse link 1 53,219,346 53,499,445 RGD:6907045
G Rps6ka3 ribosomal protein S6 kinase A3 JBrowse link X 37,469,736 37,576,055 RGD:6907045
G Rps6ka5 ribosomal protein S6 kinase A5 JBrowse link 6 124,557,892 124,735,787 RGD:6907045
G Rps6ka6 ribosomal protein S6 kinase A6 JBrowse link X 82,641,679 82,743,771 RGD:6907045
G Rras related RAS viral (r-ras) oncogene homolog JBrowse link 1 101,012,822 101,016,720 RGD:6907045
G Rras2 related RAS viral (r-ras) oncogene homolog 2 JBrowse link 1 178,940,515 179,010,257 RGD:6907045
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:1304398
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:6907045
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:6907045
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:6907045
G Stk3 serine/threonine kinase 3 JBrowse link 7 73,617,926 73,883,896 RGD:6907045
G Stk4 serine/threonine kinase 4 JBrowse link 3 160,467,552 160,546,540 RGD:6907045
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:6907045
G Taok1 TAO kinase 1 JBrowse link 10 62,542,870 62,630,341 RGD:6907045
G Taok2 TAO kinase 2 JBrowse link 1 198,301,789 198,354,601 RGD:6907045
G Taok3 TAO kinase 3 JBrowse link 12 45,037,951 45,116,593 RGD:6907045
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6907045
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6907045
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:6907045
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:6907045
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:6907045
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6907045
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:6907045
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6907045
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:6907045
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:6907045
G Tsc2 tuberous sclerosis 2 JBrowse link 10 13,962,006 13,996,684 RGD:1580517
altered Erk5 MAPK signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:2298532
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:2298532
altered extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:2293882
RGD:2298531
RGD:5133242
RGD:5133243
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:2306732
RGD:4143515
RGD:5133242
RGD:5490965
RGD:5490966
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:5133242
RGD:5133243
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:2293882
c-Jun N-terminal kinases MAPK signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:2293876
RGD:2293879
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:2293881
G Dusp10 dual specificity phosphatase 10 JBrowse link 13 104,284,660 104,321,455 RGD:2293881
G Dusp16 dual specificity phosphatase 16 JBrowse link 4 168,470,141 168,551,346 RGD:2293881
G Dusp19 dual specificity phosphatase 19 JBrowse link 3 67,849,966 67,862,475 RGD:2314491
G Dusp8 dual specificity phosphatase 8 JBrowse link 1 215,030,429 215,043,111 RGD:2293881
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:2293875
RGD:2298561
RGD:2298577
RGD:2298708
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:2293875
RGD:2298561
RGD:2298567
RGD:2298577
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:2293875
RGD:2293879
G Map3k10 mitogen activated protein kinase kinase kinase 10 JBrowse link 1 84,473,178 84,491,689 RGD:2293875
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 1 221,043,119 221,056,420 RGD:2293875
RGD:2293876
RGD:2298567
RGD:2298577
G Map3k12 mitogen activated protein kinase kinase kinase 12 JBrowse link 7 144,102,275 144,120,306 RGD:2293875
G Map3k2 mitogen activated protein kinase kinase kinase 2 JBrowse link 18 24,961,250 25,025,488 RGD:2293875
RGD:2293879
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:2293875
RGD:2293879
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:2293875
RGD:2293879
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:2293875
G Map3k9 mitogen-activated protein kinase kinase kinase 9 JBrowse link 6 105,455,461 105,518,974 RGD:2293875
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:2293875
RGD:2298561
RGD:2298567
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:2293875
RGD:2298561
RGD:2298577
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 3 81,295,023 81,304,181 RGD:1579811
RGD:2293880
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:2293880
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 10 14,259,394 14,299,276 RGD:2293880
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2293875
RGD:2298561
RGD:2298577
G Rac1 ras-related C3 botulinum toxin substrate 1 JBrowse link 12 13,090,316 13,111,841 RGD:2293876
RGD:2293879
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:11534984
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581337
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:2296020
Erk5 MAPK signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:1582263
RGD:2298532
G Map3k2 mitogen activated protein kinase kinase kinase 2 JBrowse link 18 24,961,250 25,025,488 RGD:2298532
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:2298532
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:2298532
RGD:2298794
G Sh2d2a SH2 domain containing 2A JBrowse link 2 187,218,851 187,225,000 RGD:2298532
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link 4 152,452,211 152,578,469 RGD:2298532
p38 MAPK signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1625329
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:6484113
G Bnip2 BCL2 interacting protein 2 JBrowse link 8 76,400,333 76,426,307 RGD:7240533
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:6484113
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:6484113
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:6484113
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:6484113
G Ccm2 CCM2 scaffolding protein JBrowse link 14 86,812,728 86,859,408 RGD:2293891
RGD:6484113
RGD:7240533
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:7240533
G Cdon cell adhesion associated, oncogene regulated JBrowse link 8 36,625,757 36,712,091 RGD:7240533
G Dlk1 delta like non-canonical Notch ligand 1 JBrowse link 6 133,576,513 133,583,751 RGD:7240533
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:7240533
G Dusp10 dual specificity phosphatase 10 JBrowse link 13 104,284,660 104,321,455 RGD:7240533
G Dusp16 dual specificity phosphatase 16 JBrowse link 4 168,470,141 168,551,346 RGD:7240533
G Dusp9 dual specificity phosphatase 9 JBrowse link X 157,168,143 157,172,068 RGD:7240533
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6484113
G Gadd45b growth arrest and DNA-damage-inducible, beta JBrowse link 7 11,646,283 11,648,338 RGD:6484113
G Gadd45g growth arrest and DNA-damage-inducible, gamma JBrowse link 17 13,391,474 13,393,219 RGD:6484113
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:5128786
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:2293891
RGD:2298758
RGD:6484113
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:2293891
RGD:2298758
RGD:6484113
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6484113
G Map3k10 mitogen activated protein kinase kinase kinase 10 JBrowse link 1 84,473,178 84,491,689 RGD:6484113
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 1 221,043,119 221,056,420 RGD:7240533
G Map3k20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 3 58,965,025 59,120,507 RGD:7240533
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:2293891
RGD:6484113
RGD:7240533
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:6484113
RGD:7240533
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:6484113
RGD:7240533
G Map3k6 mitogen-activated protein kinase kinase kinase 6 JBrowse link 5 151,435,679 151,448,329 RGD:6484113
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:2293891
RGD:2298758
RGD:6484113
RGD:7240533
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 17 56,109,403 56,129,925 RGD:7240533
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:2293891
RGD:6484113
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:2293891
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:2293891
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1580544
RGD:2293891
RGD:6484113
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:2293891
RGD:2302280
G Mapkapk2 mitogen-activated protein kinase-activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:2315047
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:2315047
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:2315047
G Mknk1 MAP kinase-interacting serine/threonine kinase 1 JBrowse link 5 134,691,852 134,730,887 RGD:2315047
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 JBrowse link 7 11,908,107 11,919,161 RGD:2315047
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D JBrowse link 10 72,909,550 72,945,884 RGD:7240533
G Rac1 ras-related C3 botulinum toxin substrate 1 JBrowse link 12 13,090,316 13,111,841 RGD:2293891
RGD:6484113
G Rps6ka4 ribosomal protein S6 kinase A4 JBrowse link 1 222,087,328 222,098,284 RGD:2315047
G Rps6ka5 ribosomal protein S6 kinase A5 JBrowse link 6 124,557,892 124,735,787 RGD:2315047
G Spag9 sperm associated antigen 9 JBrowse link 10 81,693,736 81,827,562 RGD:7240533
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 7 121,350,953 121,382,100 RGD:6484113
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 JBrowse link 1 1,999,574 2,017,574 RGD:6484113
G Taok1 TAO kinase 1 JBrowse link 10 62,542,870 62,630,341 RGD:6484113
RGD:7240533
G Taok2 TAO kinase 2 JBrowse link 1 198,301,789 198,354,601 RGD:6484113
RGD:7240533
G Taok3 TAO kinase 3 JBrowse link 12 45,037,951 45,116,593 RGD:6484113
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:2296020
RGD:6484113
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:6484113
RGD:7240533
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:6484113
the extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Araf A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 1,369,534 1,391,603 RGD:5686410
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1580106
RGD:1626216
RGD:5686410
G Dusp6 dual specificity phosphatase 6 JBrowse link 7 41,475,163 41,479,393 RGD:2293881
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:5686410
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:628557
RGD:5686410
G Ksr1 kinase suppressor of ras 1 JBrowse link 10 66,323,704 66,342,469 RGD:2293880
RGD:5686410
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:70317
RGD:1626216
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:729046
RGD:1626216
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:1357969
RGD:2293879
G Map3k2 mitogen activated protein kinase kinase kinase 2 JBrowse link 18 24,961,250 25,025,488 RGD:724475
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:628468
RGD:1626216
RGD:8553011
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:628468
RGD:1626216
RGD:8553011
G Mknk1 MAP kinase-interacting serine/threonine kinase 1 JBrowse link 5 134,691,852 134,730,887 RGD:2315047
RGD:8553011
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 JBrowse link 7 11,908,107 11,919,161 RGD:2315047
G Nras neuroblastoma RAS viral oncogene homolog JBrowse link 2 205,553,119 205,563,716 RGD:5686410
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2293882
RGD:2302807
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1642529
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1642630
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:70317
RGD:1580106
RGD:1626216
RGD:5686410
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:2315047
G Rps6ka2 ribosomal protein S6 kinase A2 JBrowse link 1 53,219,346 53,499,445 RGD:2315047
G Rps6ka3 ribosomal protein S6 kinase A3 JBrowse link X 37,469,736 37,576,055 RGD:2315047
G Rps6ka4 ribosomal protein S6 kinase A4 JBrowse link 1 222,087,328 222,098,284 RGD:2315047
G Rps6ka5 ribosomal protein S6 kinase A5 JBrowse link 6 124,557,892 124,735,787 RGD:2315047
G Rps6ka6 ribosomal protein S6 kinase A6 JBrowse link X 82,641,679 82,743,771 RGD:2315047
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:1304283
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:1643182
G Smad1 SMAD family member 1 JBrowse link 19 32,182,942 32,248,694 RGD:1643230
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581337
G Tsc2 tuberous sclerosis 2 JBrowse link 10 13,962,006 13,996,684 RGD:1580097

Pathway Gene Annotations

Disease Annotations Associated with Genes in the mitogen activated protein kinase signaling pathway
Disease TermsGene Symbols
2-HydroxyglutaricaciduriaSos2
22q11 Deletion SyndromeFgf8
46,XY Sex Reversal 6Map3k1
Abnormalities, MultipleCacna1c , Cacna1g , Cdc42 , Chuk , Fgfr2 , Fgfr3 , Kras , Mapk1 , Nf1 , Ntf4 , Pdgfrb , Pla2g6
Abortion, SpontaneousFgf7 , Il1b , Tgfb1 , Tgfbr1
Acanthosis NigricansFgfr3
AchondroplasiaFgfr3
Achondroplastic DwarfismFgfr3
Acne VulgarisTnf , Tnfrsf1a
AcrocephalosyndactyliaFgfr1 , Fgfr2 , Fgfr3
Acromicric DysplasiaTgfb1
Acute Coronary SyndromeHspa1a , Hspa8 , Tnf
Acute Kidney InjuryDdit3 , Egf , Egfr , Fas , Hspa1a , Hspa8 , Il1a , Il1b , Myc , Tgfb1 , Tnf , Tnfrsf1a , Tp53
Acute Lung InjuryEgfr , Fas , Faslg , Il1b , Ngf , Pak1 , Pla2g2a , Tgfb1 , Tnf
Acute-Phase ReactionDdit3
AdenocarcinomaEgfr , Erbb2 , Fgf9 , Hspa8 , Il1b , Kras , Myc , Nfkb1 , Tgfb1 , Tnf , Tp53
Adenocarcinoma of EsophagusFas , Tp53
Adenocarcinoma of LungBraf , Egfr , Erbb2 , Hras , Hspb1 , Kras , Map2k1 , Myc , Ppp3ca , Rasa1 , Sos1 , Tp53
Adenocarcinoma, Bronchiolo-AlveolarEgfr , Kras , Tp53
Adenocarcinoma, Clear CellDaxx , Tp53
Adenocarcinoma, ColonDaxx
Adenocarcinoma, FollicularKras
AdenomaCacna1d , Kras , Nf1 , Tp53
Adenoma, Liver CellHras , Kras
Adenomatous Polyposis ColiAkt1 , Egfr
Adrenal Gland NeoplasmsCdc42 , Prkaca , Tp53
Adrenal InsufficiencyPla2g2a
Adrenocortical CarcinomaBraf , Daxx , Egfr , Tp53
Adrenocortical Carcinoma, HereditaryTp53
Adrenocortical Carcinoma, PediatricTp53
Aggressive PeriodontitisIl1r2
Aging, PrematureFgf23 , Mapt , Tp53
AgranulocytosisIl1b
AIDS Dementia ComplexIl1b , Pdgfb
AIDS-Associated NephropathyEgf
Aland Island Eye DiseaseCacna1f
AlbuminuriaIl1b , Tnf
AlopeciaBdnf
Alveolar Bone LossTnf
Alveolitis, Extrinsic AllergicIl1a , Il1b , Tnf , Tnfrsf1a
Alzheimer DiseaseAkt1 , Atf2 , Bdnf , Casp3 , Cdc42 , Egf , Egfr , Elk1 , Fas , Fgf1 , Fgfr1 , Hras , Hspa1a , Hspa1b , Hspb1 , Ikbkb , Il1a , Il1b , Mapk10 , Mapk14 , Mapk8 , Mapk9 , Mapt , Ngf , Ntf3 , Ntrk1 , Ntrk2 , Pak1 , Pdgfb , Ptpn5 , Shc1 , Tnf , Tp53 , Tsc2
AmeloblastomaBraf
AmnesiaBdnf , Il1a , Ngf
Amphetamine-Related DisordersAkt1 , Arrb2 , Bdnf , Fos , Map2k5 , Rela
Amyloid NeuropathiesDusp1
AmyloidosisTnf , Tnfrsf1a
Amyotrophic Lateral SclerosisAkt1 , Casp3 , Mapk14 , Pla2g4a , Tp53
Amyotrophic Lateral Sclerosis 1Fgf6 , Fos , Jund , Pdgfa , Shc1 , Tnf
AnemiaIl1b , Tnf , Tnfrsf1a
Anemia, AplasticFas , Faslg , Tgfb1 , Tnf
Anemia, Hypochromic MicrocyticTnf
Anemia, Iron-DeficiencyTnf
Anemia, Nonspherocytic Hemolytic, due to G6pd DeficiencyIkbkg
Anemia, RefractoryTnf
Anemia, Sickle CellTgfb1 , Tnf
AnetodermaTgfb1
AneurysmTgfbr2
Aneurysm, DissectingTgfbr1 , Tgfbr2
Angina, StableTnf
Angina, UnstableAkt1 , Bdnf
AngiomyolipomaTsc2
AnkylosisFgfr2
AnorexiaIl1a , Il1b , Tnf , Tnfrsf1a
Anorexia NervosaBdnf
AnoxiaAtf4 , Bdnf , Casp3
AnthracosisIl1a , Il1b , Tnf
Anti-Glomerular Basement Membrane DiseaseDusp1 , Il1b , Mapk14 , Mapk8 , Tnf
Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisFas , Tnf , Tnfrsf1a
Antley-Bixler Syndrome PhenotypeFgfr2
ANTLEY-BIXLER SYNDROME WITHOUT GENITAL ANOMALIES OR DISORDERED STEROIDOGENESISFgfr1 , Fgfr2
Anxiety DisordersFos , Tnf
Aortic AneurysmTgfbr1 , Tgfbr2
Aortic Aneurysm, AbdominalMapk8
Aortic Aneurysm, Familial Thoracic 1Tgfbr2
Aortic Aneurysm, Familial Thoracic 3Tgfbr2
Aortic Aneurysm, ThoracicFas , Tgfb2 , Tgfbr1 , Tgfbr2
Aortic Valve InsufficiencyEgfr , Tgfb1 , Tgfb2
Aortic Valve StenosisEgfr , Ppp3cb
Aortic Valve, Calcification ofAkt1
Aplasia Cutis Congenita with Epibulbar DermoidsKras
Aplasia of Lacrimal and Salivary GlandsFgf10
Arrhythmias, CardiacCacna1c , Cacnb2 , Map2k4
Arrhythmogenic Right Ventricular DysplasiaTgfb3
Arrhythmogenic Right Ventricular Dysplasia, Familial, 1Tgfb3
Arsenic PoisoningGadd45b , Hspa1b , Il1a , Il1b , Tnf , Tp53
ArteriosclerosisDusp1 , Faslg , Il1b , Mapk9 , Rela , Tgfb1 , Tgfbr2 , Tnfrsf1a
Arteriovenous FistulaArrb1 , Arrb2 , Fgf2
Arteriovenous MalformationsRasa1
Arthritis, ExperimentalAkt1 , Arrb1 , Arrb2 , Cdc42 , Egfr , Faslg , Fgf8 , Fgfr1 , Ikbkb , Ikbkg , Il1a , Il1b , Nras , Tgfbr2 , Tnf , Tnfrsf1a
Arthritis, InfectiousTnf
Arthritis, JuvenileCd14 , Ddit3 , Dusp1 , Dusp2 , Dusp4 , Fos , Gadd45a , Il1a , Jun , Kras , Mapk1
Arthritis, PsoriaticTnf
Arthritis, RheumatoidFas , Faslg , Hspb1 , Il1a , Il1b , Pdgfb , Rasgrp1 , Tnf , Traf6
AsbestosisDdit3 , Tnf
Aspergillosis, Allergic BronchopulmonaryIl1a , Tnf , Tnfrsf1a
AsphyxiaJun
AsthmaBdnf , Cd14 , Chuk , Egfr , Fas , Il1a , Il1b , Ngf , Ntf3 , Ntf4 , Ntrk1 , Pdgfb , Pla2g4a , Tgfb1 , Tnf , Tnfrsf1a
Asthma, OccupationalTgfb1 , Tnf
AstrocytomaAkt1 , Braf , Fgfr1 , Kras , Map2k3 , Nf1 , Ntrk2 , Tp53
AtaxiaBdnf , Cacna1a , Cacna2d2 , Cacnb4
Atelosteogenesis Type 3Flnb
Atelosteogenesis, type 1Flnb
AtherosclerosisAkt1 , Faslg , Fgf21 , Hspa1a , Hspa1b , Il1b , Ngf , Pdgfrb , Pla2g2a , Tnf
Atrial FibrillationTnf
AtrophyMapk3
Attention Deficit Disorder with HyperactivityBdnf , Ntrk2
Atypical Mycobacteriosis, Familial, X-Linked 1Ikbkg
Auditory Neuropathy, Autosomal Dominant, 1Tgfbr1
Autism Spectrum DisorderBdnf , Dusp14 , Mapk11 , Mapk12 , Mapk3 , Mapk8ip2 , Mef2c , Taok2 , Tsc2
Autistic DisorderBdnf , Cacna1c , Cacna1h , Hras , Mef2c , Nf1 , Ntf3 , Ntf4 , Ntrk2 , Pla2g4a , Prkcb , Tnf , Tsc2
Autoimmune DiseasesFas , Tgfb2 , Tnfrsf1a
Autoimmune Lymphoproliferative SyndromeFas , Faslg , Nras
Autoimmune Lymphoproliferative Syndrome, Type IAFas
Autoimmune Lymphoproliferative Syndrome, Type IVKras , Nras
BacteremiaMapkapk3
Bacterial InfectionsCasp3
Bacterial KeratitisIl1r1
Balkan NephropathyTp53
Bardet-Biedl SyndromeAkt3
Barrett EsophagusRela
Basal Ganglia Calcification, Idiopathic, 4Pdgfrb
Basal Ganglia Calcification, Idiopathic, 5Pdgfb
Basal Ganglia DiseasesPdgfb , Pdgfrb
Behcet SyndromeFas , Ikbkg , Il1b , Tgfb1 , Tnf , Tnfrsf1a
Benign Skin NeoplasmsHras
Bent Bone Dysplasia SyndromeFgfr2
BerylliosisTgfb1 , Tnf
Beta-ThalassemiaIl1a , Tnf
Bile Duct NeoplasmsEgfr
Biliary AtresiaCd14
Biliary Tract DiseasesFgf2
Biliary Tract NeoplasmsFaslg , Prkacb
Bipolar DisorderAkt1 , Bdnf , Cacna1c , Cdc42 , Ntrk1 , Ntrk2
BLEEDING DISORDER, PLATELET-TYPE, 18Rasgrp2
Blood Platelet DisordersPla2g4a
Body WeightBdnf , Map2k5
Bone DiseasesFgf2 , Tgfbr2
Bone Diseases, DevelopmentalChuk , Fgfr3 , Flnb , Rps6ka3 , Tgfb2 , Tp53
Bone Diseases, EndocrinePdgfa
Bone Marrow NeoplasmsTp53
Bone NeoplasmsTgfbr2
Boomerang DysplasiaFlnb
Brain DeathMap2k4 , Map2k6
Brain DiseasesTsc2
Brain Diseases, MetabolicFas
Brain EdemaTnf
Brain InfarctionFgf2 , Il1b , Pdgfb
Brain InjuriesAkt1 , Bdnf , Casp3 , Cd14 , Dusp5 , Elk1 , Fas , Fgf2 , Fos , Hspa1a , Hspb1 , Il1a , Il1b , Il1r1 , Jun , Pdgfa , Pdgfb , Pdgfra , Pdgfrb , Ppp3ca , Rela , Tnf , Tnfrsf1a
Brain IschemiaAkt1 , Bdnf , Casp3 , Ddit3 , Dusp6 , Fas , Faslg , Fgf1 , Hspa1b , Hspa8 , Il1a , Il1b , Jun , Map2k1 , Mapk1 , Mapk3 , Mapk8 , Mapt , Nfkb1 , Pak1 , Pla2g4a , Prkaca , Prkacb , Prkca , Rela , Tgfb1 , Tnf , Tnfrsf1a , Tp53
Brain NeoplasmsRela , Tp53
Breast AdenocarcinomaAkt1 , Kras , Tp53
Breast NeoplasmsAkt1 , Akt2 , Casp3 , Cdc25b , Crkl , Ddit3 , Dusp1 , Dusp6 , Egfr , Erbb2 , Fas , Faslg , Fgf10 , Fgf2 , Fgf3 , Fgf4 , Fgf8 , Fgfr1 , Fgfr2 , Fgfr3 , Flna , Fos , Hras , Hspa1b , Ikbkb , Il1b , Jun , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k4 , Map2k7 , Map3k1 , Mapk1 , Mapt , Mecom , Myc , Pak1 , Pak2 , Pdgfa , Pdgfra , Pdgfrb , Pla2g4a , Prkca , Raf1 , Rela , Stmn1 , Tgfb1 , Tnf , Tp53 , Tsc2
Breast-Ovarian Cancer, Familial, Susceptibility To, 1Akt1
Bronchial HyperreactivityCd14 , Il1b , Ngf , Tnf
BronchiectasisIl1b , Tnf
Bronchiectasis with or without Elevated Sweat Chloride 1Tnfrsf1a
Bronchiectasis with or without Elevated Sweat Chloride 2Tnfrsf1a
Bronchiectasis with or without Elevated Sweat Chloride 3Tnfrsf1a
BronchiolitisIl1b
Bronchiolitis, ViralCd14 , Tnf
Bronchopulmonary DysplasiaIl1b
Brugada SyndromeCacna1c , Cacna2d1 , Cacnb2
Brugada Syndrome 3Cacna1c
Brugada Syndrome 4Cacnb2
Bulimia NervosaBdnf
Burkitt LymphomaMyc
BurnsCasp3 , Cd14 , Fgfr1 , Il1a , Il1b , Ngf , Pla2g4a , Tnf
Burns, ChemicalFgfr2 , Il1a , Il1b , Il1r1
CachexiaIl1b , Tgfb1 , Tnf , Tnfrsf1a
Cafe au lait Spots, MultipleNf1 , Sos1
Cafe-au-Lait SpotsNf1
CakutHspa1b
CalcinosisCasp3 , Erbb2 , Fgf23 , Il1b , Pdgfb , Pdgfrb , Tgfb1
Camurati-Engelmann SyndromeTgfb1
Capillary Malformation-Arteriovenous MalformationRasa1
CarcinogenesisBraf , Erbb2 , Kras
CarcinomaCdc42 , Dusp6 , Egfr , Hras , Kras , Myc , Pdgfa , Rasa1 , Rasgrf2 , Stmn1 , Tgfb1 , Tgfbr2 , Tp53
Carcinoma in SituAkt1 , Pdgfra
Carcinoma, Adenoid CysticFgf16 , Fgfr4 , Hras , Map2k2 , Tp53
Carcinoma, Basal CellErbb2 , Rasa1 , Tp53
Carcinoma, Ductal, BreastAtf4 , Cacna1c , Cacna1h , Crkl , Map2k4
Carcinoma, EmbryonalFgf8
Carcinoma, EndometrioidDaxx , Egfr , Erbb2 , Fgfr2 , Kras , Pdgfra , Pdgfrb
Carcinoma, HepatocellularAkt2 , Braf , Egfr , Fgf19 , Fgf3 , Fgf4 , Fos , Hras , Hspb1 , Il1b , Jun , Kras , Myc , Pdgfb , Rac1 , Rps6ka3 , Shc1 , Srf , Tgfb1 , Tgfbr2 , Tnf , Tp53
Carcinoma, Intraductal, NoninfiltratingErbb2 , Pak2 , Prkca , Rela , Tp53
Carcinoma, Islet CellDaxx
Carcinoma, Large CellPrkca
Carcinoma, LobularErbb2 , Faslg
Carcinoma, Merkel CellMyc
Carcinoma, Non-Small-Cell LungAkt1 , Braf , Dusp3 , Egfr , Erbb2 , Faslg , Fgf9 , Fgfr1 , Hras , Il1a , Il1b , Kras , Map2k1 , Myc , Nras , Raf1 , Rela , Tnf , Tnfrsf1a , Tp53
Carcinoma, Pancreatic DuctalEgf , Faslg , Fgf2 , Hspa1a , Hspa1b , Kras , Tgfb1 , Tgfbr2 , Tsc2
Carcinoma, Renal CellAkt1 , Casp3 , Egfr , Erbb2 , Fas , Faslg , Fgf2 , Fgfr1 , Hspb1 , Jun , Kras , Map2k1 , Myc , Pak1 , Pdgfra , Pdgfrb , Rela , Tnf , Tnfrsf1a , Tp53 , Tsc2
Carcinoma, Small CellTnf , Tp53
Carcinoma, Squamous CellAkt1 , Dusp1 , Egfr , Fas , Fgf7 , Fgfr1 , Fgfr2 , Hras , Hspa8 , Hspb1 , Kras , Mapk1 , Mapk3 , Myc , Rasa1 , Tgfb1 , Tnfrsf1a , Tp53 , Tsc2
Carcinoma, Squamous Cell of Head and NeckAkt1 , Egfr , Rasgrp3 , Tp53
Carcinoma, Transitional CellCasp3 , Daxx , Egfr , Erbb2 , Fas , Faslg , Fgf1 , Fgf2 , Fgfr2 , Fgfr3 , Hras , Kras , Nras , Pak1 , Pla2g4a , Tnf , Tp53
CarcinosarcomaTgfb1
Cardiac Complexes, PrematureCacna1c , Cacnb2
Cardiac Conduction Defect, NonspecificCacnb2
Cardiac FibrosisPak1 , Tgfb1
Cardiac Valvular Dysplasia, X-LinkedFlna
Cardiofaciocutaneous SyndromeBraf , Hras , Kras , Map2k1 , Map2k2
Cardiofaciocutaneous Syndrome 2Kras
CARDIOFACIOCUTANEOUS SYNDROME 3Map2k1
Cardiofaciocutaneous Syndrome 4Map2k2
CardiomegalyAkt1 , Egfr , Fgf2 , Fgf21 , Il1b , Map2k5 , Map2k6 , Mapk1 , Mapk8 , Myc , Pak1 , Pdgfrb , Ppp3ca , Prkca , Prkcb , Rac1 , Rela , Shc1 , Srf , Tgfb1 , Tnf
CardiomyopathiesAkt1 , Fas , Faslg , Flnc , Il1a , Il1b , Kras , Mapk1 , Mapk11 , Mapk14 , Mapk3 , Srf , Tnf , Tp53
Cardiomyopathy, DilatedEgfr , Erbb2 , Fas , Faslg , Kras , Map2k5 , Mef2c , Nfatc4 , Ppp3r1 , Prkca , Prkcb , Rac1 , Raf1 , Srf , Tnf
CARDIOMYOPATHY, DILATED, 1NNRaf1
CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 5Flnc
Cardiomyopathy, HypertrophicCasp3 , Hspb1 , Kras , Myc , Prkaca , Raf1 , Sos1 , Tgfb1 , Tp53
Cardiomyopathy, Hypertrophic, FamilialKras , Raf1 , Sos1
Cardiomyopathy, RestrictiveCacna1c , Map2k3 , Map2k6 , Mapk14
Cardiovascular AbnormalitiesFgf8 , Map2k1 , Srf
Cardiovascular DiseasesHspa1a
Cardiovirus InfectionsTnf
Carotid Artery DiseasesCd14 , Faslg , Mras , Tgfb1 , Tp53
Carotid Artery InjuriesDusp1 , Myc
Carotid AtherosclerosisFgf21
Carotid StenosisFaslg
Cartilage DiseasesFgf14
CataractFas , Fgf2 , Tp53
CATSHL SyndromeFgfr3
Cecal NeoplasmsKras , Tp53
Celiac DiseaseCd14
Cell Transformation, NeoplasticHras , Jun , Kras , Mapk8 , Myc , Nfkb1 , Rac1 , Rela , Tgfb1 , Tp53
Central Nervous System NeoplasmsTp53
Cerebral HemorrhageBdnf , Casp3 , Cd14 , Nfkb1 , Nfkb2 , Rela
Cerebral InfarctionTnf
Ceroid Lipofuscinosis, Neuronal, 6Mapk1 , Mapk3
Cervical Intraepithelial NeoplasiaFaslg , Rela
Charcot-Marie-Tooth DiseaseHspb1 , Ntrk2
Charcot-Marie-Tooth Disease, Type 2FHspb1
Chemotherapy-Induced Febrile NeutropeniaTp53
Chest TraumaFas
Chlamydia InfectionsTnf
ChloracneEgfr , Gadd45a
CholangiocarcinomaEgfr , Erbb2 , Faslg , Fgf2 , Fgfr2 , Kras , Prkaca , Prkacb , Tgfb1 , Tgfbr2 , Tp53
CholangitisTgfb2
CholecystolithiasisPla2g2a
CholestasisCd14 , Il1a , Mapk13 , Mapk14 , Pdgfb , Rela , Tnf
Cholestasis, ExtrahepaticPdgfrb
CholesteatomaIl1a , Il1b
Cholesteatoma, Middle EarFgf2 , Il1a , Il1r1 , Rela , Tnf , Tp53
ChondrosarcomaFgfr3
Chondrosarcoma, MesenchymalIl1a , Pdgfra
ChoreaCacna2d2
ChorioamnionitisIl1a , Tgfb1
ChoriocarcinomaFgf8 , Pdgfb , Pdgfrb
Choroid Plexus CarcinomaTp53
Choroidal NeovascularizationFgf2 , Ikbkb
Chromosome 17 DeletionTp53
Chromosome 17q12 Deletion SyndromeDusp14
Chromosome BreakageMyc
Chronic Allograft DysfunctionTnf
Chronic Allograft NephropathyPdgfa , Pdgfb , Pdgfra , Pdgfrb
Chronic Cerebral HypoperfusionMapk14
Chronic Lymphoid LeukemiaMyc
Chronic Myeloproliferative DisorderPdgfrb
Chronic PainBdnf , Ntrk2
Chronic PeriodontitisRac2
Chronic UveitisFas
Clear-Cell Metastatic Renal Cell CarcinomaMyc
Cleft LipFgf1 , Fgf10 , Fgf2 , Fgf3 , Fgf7 , Fgf8 , Fgf9 , Fgfr1 , Fgfr2 , Fgfr3 , Myc
Cleft PalateChuk , Fgf10 , Fgf2 , Fgf3 , Fgf7 , Fgf8 , Fgf9 , Fgfr1 , Fgfr2 , Fgfr3 , Flna , Flnb , Myc , Pdgfra , Tgfb1 , Tgfb2 , Tgfb3
Cleft Palate, Isolated, and Mental RetardationPdgfra
ClonorchiasisFas , Faslg
ClubfootFlnb
Cocaine-Related DisordersBdnf , Fgf2 , Fos , Jund , Mapk1 , Mapk3 , Ngf , Ntrk2 , Rps6ka5
Cocoon SyndromeChuk
Coffin-Lowry SyndromeRps6ka3
Cognition DisordersBdnf , Fgf14 , Mapk14 , Mapt
ColitisArrb1 , Bdnf , Chuk , Dusp1 , Ikbkb , Il1b , Ntrk1 , Ntrk2 , Pla2g2a , Rela , Tnf
Colitis, ExperimentalFas , Pdgfra , Pdgfrb , Tnf , Tnfrsf1a
Colitis, UlcerativeTp53
Colonic NeoplasmsAkt1 , Akt2 , Braf , Cacna2d1 , Crkl , Egfr , Erbb2 , Fas , Fgfr3 , Hspa2 , Hspb1 , Ikbkb , Il1b , Jun , Kras , Map2k3 , Map2k6 , Mecom , Myc , Nfkb1 , Nras , Pdgfrb , Pla2g2a , Rela , Tgfbr2 , Tnf , Tnfrsf1a , Tp53
Color Vision DefectsBdnf
Colorectal Cancer, Hereditary Nonpolyposis, Type 6Tgfbr2
Colorectal NeoplasmsAkt1 , Braf , Egfr , Fgfr3 , Flnc , Hspa8 , Kras , Nras , Pla2g2a , Prkcb , Tgfb1 , Tgfbr1 , Tgfbr2 , Tnf , Tp53
Colorectal Neoplasms, Hereditary NonpolyposisTgfbr1 , Tgfbr2
Common ColdIl1a , Il1b
Common Variable ImmunodeficiencyNfkb2
Cone Dystrophy 3Cacna2d4
Cone-Rod Dystrophy, X-Linked, 3Cacna1f
Congenital AbnormalitiesRac2
Congenital Central Hypoventilation SyndromeBdnf
Congenital Idiopathic Intestinal PseudoobstructionFlna
Conjunctivitis, AllergicIl1b , Pla2g2a , Tgfb1
Conjunctivitis, ChronicFas
Contrast-Induced NephropathyIl1b
Copper-Overload CirrhosisCasp3 , Tgfb1
Corneal EdemaIl1a
Corneal NeovascularizationFas , Fgf2
Corneal UlcerNgf , Tnf
Coronary Artery DiseaseAkt1 , Cd14 , Fgf2 , Il1b , Mras , Ngf , Tgfb1 , Tnf , Tnfrsf1a , Traf6
Coronary DiseaseCd14 , Fgf2 , Hspa1a , Il1b
Coronary OcclusionHspa1a
Coronary RestenosisMapk1 , Myc , Tnf , Tp53
Costello SyndromeBraf , Hras , Kras , Map2k1 , Map2k2
CoughTnf
Craniocerebral TraumaIl1a
Cranioectodermal DysplasiaTgfb3
Craniofacial AbnormalitiesEgfr , Fgf3 , Fgf8 , Fgfr1 , Fgfr2 , Pdgfra , Tgfb2 , Tgfbr2 , Tp53
Craniofacial DysostosisFgfr2
CraniopharyngiomaBraf , Pdgfra
CraniosynostosesFgfr1 , Fgfr2 , Fgfr3 , Flna
Creutzfeldt-Jakob SyndromeIl1a
Crohn DiseaseTnf , Tnfrsf1a
Crouzon Syndrome with Acanthosis NigricansFgfr3
CryoglobulinemiaTnf
Cryptogenic Organizing PneumoniaTnfrsf1a
CryptorchidismCasp3 , Rela
Currarino TriadMap3k13
Cutis Gyrata Syndrome of Beare And StevensonFgfr2
CyanosisTgfb2
Cystadenocarcinoma, SerousTp53
Cystadenoma, MucinousDaxx
Cystadenoma, SerousDaxx
Cystic FibrosisCd14 , Hspa1a , Il1a , Il1b , Tgfb1 , Tnf , Tnfrsf1a
CystitisBdnf , Il1b , Ngf , Rela , Tnf
Cystitis, InterstitialNgf , Tnf
Cytomegalovirus RetinitisTnf , Tnfrsf1a
DeafnessBdnf , Cacna1d
Deafness, Congenital, with Inner Ear Agenesis, Microtia, and MicrodontiaFgf3
Death, SuddenMap2k5
Death, Sudden, CardiacCacna1c
DementiaEgfr , Mapt
Dementia, VascularBdnf , Fgfr1 , Hspa1a , Il1b , Tp53
Demyelinating DiseasesFgf2 , Fgfr1 , Fgfr3 , Myc , Tp53
Depressive DisorderBdnf , Fgf2 , Fgfr1 , Il1b , Jun , Ngf , Ntrk2 , Pla2g2a
Depressive Disorder, MajorBdnf , Dusp1 , Hspa1a , Hspa1l , Ntrk2
DermatitisFgf2 , Ikbkb , Pla2g4a , Tnf
Dermatitis HerpetiformisTnf
Dermatitis, Allergic ContactIl1a , Tnf
Dermatitis, AtopicBdnf , Il1b , Mapk8 , Ngf , Ntrk1 , Tgfb1 , Tnf
Dermatitis, ContactDdit3 , Dusp1 , Hspb1
DermatofibrosarcomaPdgfb
DermatomyositisFas , Il1a , Il1b , Tnf
Developmental DisabilitiesAkt3 , Cacna1a , Ntrk2 , Rps6ka3
Diabetes Insipidus, NephrogenicPrkca
Diabetes MellitusRac1
Diabetes Mellitus, ExperimentalAkt1 , Bdnf , Casp3 , Dusp1 , Egfr , Fas , Faslg , Fgf2 , Fgf21 , Hras , Ikbkb , Il1a , Il1b , Map2k3 , Map2k6 , Mapk1 , Mapk3 , Mef2c , Myc , Nfkb2 , Ngf , Ntrk1 , Pdgfb , Pdgfrb , Prkca , Prkcb , Rap1b , Rasgrf1 , Rela , Tgfb1 , Tgfb2 , Tnf , Tnfrsf1a , Tp53 , Tsc2
Diabetes Mellitus, Type 1Casp3 , Cd14 , Ddit3 , Dusp1 , Egfr , Fas , Faslg , Fgf21 , Il1a , Il1b , Il1r1 , Tgfb1 , Tnf
Diabetes Mellitus, Type 2Akt1 , Akt2 , Bdnf , Casp3 , Egfr , Fas , Faslg , Fgf2 , Fgf21 , Fgfr1 , Hspa1b , Ikbkb , Il1b , Mapk8ip1 , Nfkb1 , Prkcb , Rela , Tgfb1 , Tgfbr2 , Tnf , Tnfrsf1a
Diabetes, GestationalFgf2
Diabetic AngiopathiesCasp3 , Fas , Faslg , Rela , Tnf
Diabetic CardiomyopathiesErbb2 , Tnf
Diabetic EncephalopathiesDusp1 , Ngf
Diabetic FootHspa1b
Diabetic NephropathiesBdnf , Casp3 , Egf , Fas , Faslg , Fgf2 , Fgf21 , Fgf23 , Hspa1a , Hspa1b , Hspa8 , Hspb1 , Il1b , Mapk1 , Mapk14 , Ntrk2 , Pdgfa , Pdgfb , Pdgfrb , Prkcb , Rela , Tgfb1 , Tgfbr2 , Tnf , Tnfrsf1a , Tp53
Diabetic NeuropathiesBdnf , Casp3 , Fgf2 , Il1b , Mapk14 , Ngf , Ntf3 , Ntrk1 , Tgfb1 , Tgfb2 , Tgfb3 , Tnf
Diabetic RetinopathyBdnf , Casp3 , Egfr , Fgf2 , Hras , Il1a , Il1b , Ngf , Tnf
Diaphyseal Dysplasia 1, ProgressiveTgfb1
DiarrheaCd14 , Il1a
DiGeorge SyndromeCrkl , Fgf8
Dilatation, PathologicTgfb1
Disease Models, AnimalAkt1 , Erbb2 , Fas , Fos , Il1b , Kras , Mapk1 , Mapk3 , Mapk8 , Mapk9 , Mapt , Prkcg , Tnf , Tp53
Disease ProgressionAtf2 , Egfr , Erbb2 , Fgf2 , Hras , Myc
Disseminated Intravascular CoagulationTnf
Down SyndromeNtf3
Drug EruptionsBdnf
Drug HypersensitivityFaslg , Hspa1a , Hspa1l , Tnf
Drug Hypersensitivity SyndromeHspa1l , Il1b
Drug-induced agranulocytosisIl1b
Drug-Induced Immune ThrombocytopeniaIl1a , Il1b
Drug-Induced Liver InjuryCdc25b , Fas , Gadd45a , Hspa8 , Il1a , Il1b , Il1r2 , Tnf
Drug-induced NeutropeniaIl1a , Tp53
Drug-Related Side Effects and Adverse ReactionsTp53
Dry Eye SyndromesIl1b , Tgfb1 , Tnf
Duodenal UlcerPla2g4a , Tgfb1
DwarfismFgfr3
DysarthriaCacna1a
Dysembryoplastic Neuroepithelial TumorBraf
DysgerminomaFgfr2
Dyskeratosis Congenita, Autosomal RecessiveTp53
Dyskinesia, Drug-InducedCacna1d , Rasgrf1 , Rela
DyskinesiasRasgrf1
Dystonia 12Pla2g6
Dystonia 23Cacna1b
Dystonia-Parkinsonism, Adult-OnsetPla2g6
Eales DiseaseIl1b , Tnf
Ectodermal Dysplasia, Anhidrotic, with Immunodeficiency, Osteopetrosis, and LymphedemaIkbkg
Ectodermal Dysplasia, Hypohidrotic, with Immune DeficiencyIkbkg
EctrodactylyMap3k20
EczemaCd14
EdemaCasp3 , Il1b , Map2k6 , Tnf
Ehlers-Danlos SyndromeTgfb1
EmphysemaTnf , Tp53
EncephalitisIl1b , Rela , Tnf
Encephalocraniocutaneous LipomatosisFgfr1
Encephalomyelitis, Autoimmune, ExperimentalBdnf , Cacna1b , Casp3 , Dusp10 , Fgf2 , Mapt , Ngf , Ntrk1 , Pdgfb , Pdgfra , Pdgfrb , Tgfb1 , Tgfb2
End Stage Liver DiseaseTnfrsf1a
Endodermal Sinus TumorFgf8
Endometrial HyperplasiaCdc25b , Kras
Endometrial NeoplasmsCdc25b , Erbb2 , Fgf1 , Fgf2 , Fgf7 , Fgfr2 , Jun , Kras , Map3k4 , Myc , Prkca , Tnfrsf1a , Tp53
EndometriosisDusp1 , Egfr , Fgfr2 , Fos , Il1r1 , Kras , Nr4a1 , Ntrk1 , Pla2g2a , Rasgrp1 , Tgfb2 , Tnf
EndometritisIl1a
Endomyocardial FibrosisTgfb1
EndophthalmitisFas , Il1b , Tnf
EndotoxemiaAtf2 , Casp3 , Cd14 , Fas , Il1a , Il1b , Mapk14 , Tnf
EntamoebiasisIl1b
EnterocolitisIl1a , Il1b
Enterocolitis, NecrotizingCd14 , Egf , Ikbkg , Il1b , Tnf
Enterocolitis, NeutropenicIl1b
Enterovirus InfectionsTnfrsf1a
EosinophiliaPdgfra
Eosinophilic EsophagitisTgfb1
Epidermal NevusFgfr3 , Hras , Kras , Nras
Epilepsies, PartialBdnf , Cacna1h
EpilepsyAkt1 , Bdnf , Cacna1c , Flna , Fos , Mef2c , Ntrk2 , Tsc2
Epilepsy, AbsenceCacna1a , Cacna1h , Cacna2d2 , Cacng3
Epilepsy, GeneralizedCacna1a , Cacnb4 , Mapk10
Epilepsy, Idiopathic GeneralizedCacnb4
Epilepsy, Temporal LobeCacna1a , Cdc42 , Ntrk2 , Rasgrf1
Epilepsy, Tonic-ClonicBdnf , Fgf2 , Ngf , Ntf3
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 42Cacna1a
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 47Fgf12
Epileptic Encephalopathy, Lennox-Gastaut TypeMapk10
Episodic AtaxiaCacnb4
Episodic Ataxia with NystagmusCacna1a
Episodic Ataxia, Type 5Cacnb4
Erectile DysfunctionAkt1 , Casp3 , Fgf2 , Tgfb1 , Tnf
Erythema NodosumTnf
Escherichia Coli InfectionsNtrk2
Esophageal NeoplasmsEgfr , Erbb2 , Fas , Faslg , Map3k3 , Myc , Tgfbr2 , Tp53
Esophageal Squamous Cell CarcinomaEgfr , Tp53
EsophagitisTnf
Esophagitis, PepticEgfr , Tnf
Essential TremorMapt
Exfoliation SyndromeCacna1a
Experimental SeizuresRasgrf1
Eye AbnormalitiesTgfb2 , Tgfbr2
Eye BurnsIl1b
Eye DiseasesTnf
Eye InjuriesFgf2
Eye Injuries, PenetratingFgf2
Fabry DiseaseIl1a
Facial Nerve InjuriesAtf2
Familial Mediterranean FeverIl1b , Tnfrsf1a
Familial Medullary Thyroid CarcinomaNtrk1
Fanconi AnemiaTnf
Farmer's LungTnf
FatigueTgfbr2
Fatty LiverFgf21 , Il1b , Mapk8 , Myc , Nfkb1 , Rela , Shc1 , Tnf
Femoral FracturesFgf2 , Fgfr1 , Il1a , Nf1
Fetal DeathPdgfra
Fetal DiseasesChuk , Prkcb
Fetal Growth RetardationCasp3 , Dusp1 , Dusp5 , Elk1 , Il1a , Pdgfa , Pdgfb
FeverHspb1 , Il1a , Il1b , Pla2g4a , Tnf , Tnfrsf1a
Fibromatosis, AggressiveTnf
Fibromatosis, Congenital GeneralizedPdgfrb
Fibromatosis, GingivalSos1
Fibromatosis, Gingival, 1Sos1
FibrosarcomaCdc42 , Nf1 , Tnfrsf1a
FibrosisAkt1 , Il1b , Map2k7 , Pdgfb , Tgfb1 , Tnf
Fibrous Dysplasia of BoneFos
Filaminopathy, Autosomal DominantFlnb , Flnc
Fleck Retina, Familial BenignPla2g5
Foot Deformities, CongenitalFgfr1
Forney Robinson Pascoe SyndromeMap3k7
Fractures, BoneFgf2 , Tgfbr2
Frontometaphyseal DysplasiaFlna
FRONTOMETAPHYSEAL DYSPLASIA 2Map3k7
Frontotemporal DementiaMapt
Frontotemporal Lobar DegenerationBdnf
GalactosemiasDdit3
Gallbladder NeoplasmsEgf , Egfr , Erbb2 , Faslg , Fgf2 , Il1b , Kras , Tgfb1 , Tp53
GastritisTnf
Gastritis, AtrophicIl1b
Gastroesophageal RefluxPla2g2a
Gastrointestinal NeoplasmsErbb2
Gastrointestinal Stromal TumorsPdgfra
Genetic Diseases, InbornCacna1a , Cacna1c , Cacna1e , Cacna1g , Cdc42 , Fgfr2 , Fgfr3 , Mapk1 , Nf1 , Ntf4 , Ntrk1 , Pdgfrb , Pla2g6
Genetic Predisposition to DiseaseIl1b
GerminomaBraf
Giant Pigmented Hairy NevusHras , Nras
Gingival HyperplasiaFgf7 , Pdgfb
GlaucomaAtf2 , Bdnf , Fas , Ngf , Ntrk1 , Ntrk2 , Tgfb2 , Tnf
Glaucoma 1, Open Angle, ONtf4
Glaucoma, Open-AngleTnf
Glaucoma, Primary Open AngleBdnf , Tnf , Tp53
GlioblastomaAkt1 , Dusp6 , Egfr , Erbb2 , Il1b , Map2k3 , Myc , Nf1 , Pdgfb
GliomaAkt2 , Braf , Egfr , Erbb2 , Fas , Fgf2 , Fgfr1 , Nf1 , Ntrk1 , Ntrk2 , Raf1 , Stmn1 , Tnf , Tp53
GliosisBdnf , Fgf2 , Mapk1 , Mapk3 , Mapt
GlomerulonephritisFas , Fos , Il1a , Il1b , Il1r1 , Jund , Mapk1 , Ngf , Pdgfb , Tnf , Tnfrsf1a
Glomerulonephritis, CrescenticIl1b
Glomerulonephritis, IGACd14 , Il1a , Il1b , Ngf , Tgfb1 , Tnf , Tnfrsf1a
Glomerulonephritis, MembranoproliferativeIl1b , Tgfbr2
Glomerulonephritis, MembranousIl1b
GlomerulosclerosisIl1b
Glomerulosclerosis, Focal SegmentalHspb1 , Il1b , Tgfb1 , Tnf , Tnfrsf1a
Glucose IntoleranceDusp1
Glucosephosphate Dehydrogenase DeficiencyIkbkg
GoutCd14 , Il1b
Graft vs Host DiseaseFas , Faslg , Hspa1a , Hspa1b , Hspa8 , Il1a , Pdgfb , Tp53
Gram-Negative Bacterial InfectionsIl1b
Graves DiseaseFas , Il1b , Tnf , Tp53
Graves OphthalmopathyIl1a , Tnf
HamartomaTsc2
Hamartoma Syndrome, MultipleAkt1 , Egfr , Fgfr2
Hashimoto DiseaseFas
Head and Neck NeoplasmsEgfr , Mapk1 , Mapk3
Head Injuries, PenetratingFgfr1 , Pdgfb
Hearing LossBdnf , Ntf3 , Tnf
Hearing Loss, ConductiveFlna
Hearing Loss, High-FrequencyTnf
Hearing Loss, Noise-InducedBdnf , Hspa1a , Hspa1b , Hspa1l , Taok1 , Tnf
Hearing Loss, SensorineuralBdnf , Fgf3 , Ngf , Tnf
Hearing Loss, SuddenHspa1a , Hspa1b , Hspa1l , Tnf
Heart ArrestAkt1 , Cacna2d1 , Cacnb2 , Tnf
Heart Defects, CongenitalTgfb2
Heart DiseasesMapk14 , Rac2 , Tgfb1
Heart FailureArrb1 , Erbb2 , Fas , Fos , Hspb1 , Il1b , Map2k7 , Prkaca , Prkca , Prkcb , Rac1 , Srf , Tnf , Tnfrsf1a , Tp53
Heart Failure, SystolicHspa1a
Heart InjuriesIl1b
Heart Septal Defects, VentricularBraf , Fos , Tgfb3
Heart Valve DiseasesCasp3 , Il1b
Heat Stress DisordersHspa1a
Heat StrokeFos , Il1a , Il1b , Jun , Nfkb1 , Nfkb2 , Rela , Tnf
Heavy Metal ToxicityDaxx
HELLP SyndromeErbb2
HemangiomaTsc2
Hemangioma, CapillaryAkt3
HemangiosarcomaHras , Jun , Kras , Myc , Tp53
Hematologic DiseasesFas
HematuriaFos
Hemiplegic Migraine, Familial Type 1Cacna1a
HemochromatosisTnf
Hemolytic-Uremic SyndromeFos , Il1a , Il1b , Tnf
Hemophilia ATgfb1
HemorrhageFos , Il1a
Hepatic EncephalopathyTnf
HepatitisFaslg
Hepatitis CIl1b
Hepatitis C, ChronicTnfrsf1a
Hepatitis, AcuteTsc2
Hepatitis, AlcoholicTnf
Hepatitis, AutoimmuneTgfb1
Hepatitis, ChronicCasp3 , Shc1 , Tgfb1
HepatoblastomaTp53
Hepatolenticular DegenerationPpp3ca , Ppp3cb , Tnf
Hepatorenal SyndromeTnf
Hereditary Paraganglioma-Pheochromocytoma SyndromesMax
Hereditary Sensory and Autonomic NeuropathiesNgf , Ntrk1
Hernia, DiaphragmaticFgf18 , Fgf2 , Tgfb1 , Tnf
Hernia, InguinalTgfbr2
Hernia, UmbilicalFgfr1 , Fgfr2
Heroin DependenceBdnf , Fas , Ngf
Herpes ZosterTnf
Heterotopia, Periventricular, Ehlers-Danlos VariantFlna
Hidradenitis SuppurativaTnf
High MyopiaRasgrf1
Hirschsprung DiseaseCd14 , Erbb2 , Ntrk1 , Tsc2
Hirschsprung Disease 1Ntf3 , Tsc2
HirsutismCacna1g
HIV InfectionsCdc42 , Fas , Gadd45a , Hspb1 , Pla2g2a , Srf , Tnf
HIV Wasting SyndromeIl1a , Il1b , Tnf
Hodgkin DiseaseJun
HoloprosencephalyFgf8 , Fgfr1
Holoprosencephaly, Ectrodactyly, and Bilateral Cleft Lip/PalateFgfr1
Holt-Oram SyndromeTgfb2
Huntington DiseaseAtf2 , Bdnf , Dusp1 , Egfr , Elk1 , Hspa8 , Nfkb1 , Ppp3ca
Hydatidiform MolePdgfrb
HydrocephalusNtf3
HydronephrosisIl1b
Hyper-IgM Immunodeficiency, X-Linked, with Ectodermal Dysplasia, HypohidroticIkbkg
HyperaldosteronismCacna1d , Cacna1h
HyperalgesiaBdnf , Cacna1b , Cacna1h , Cacna2d1 , Dusp1 , Dusp6 , Fos , Il1a , Il1b , Il1r1 , Map2k3 , Mapk1 , Mapk3 , Mapk7 , Mapk8 , Mapk9 , Ngf , Ntf3 , Ntrk1 , Ntrk2 , Pla2g4a , Prkcb , Prkcg , Raf1 , Tnf , Tnfrsf1a
HyperbilirubinemiaTnf
HypercalcemiaTnf
HypercholesterolemiaFgf2 , Il1b
HyperemiaIl1b
Hypereosinophilic SyndromePdgfra
HyperglycemiaCacna1e , Il1a , Il1b , Pla2g4a , Prkcb , Shc1
HyperhomocysteinemiaIl1b , Ngf , Tnf
HyperkinesisFos , Ngf , Ntrk2
Hyperlipidemia, Familial CombinedFaslg
HyperlipidemiasHspa1b , Shc1 , Tgfb1
HyperoxaluriaNfkb1 , Rap1a
HyperoxiaBdnf , Fas , Pdgfra , Pdgfrb , Tgfb1 , Tnf , Tnfrsf1a
Hyperoxic Lung InjuryFgf2 , Pdgfb
HyperparathyroidismMyc
HyperphagiaNtrk2
HyperphosphatemiaFgf23
HyperplasiaAkt1 , Egfr , Hspb1 , Ikbkb , Tgfb1 , Tgfbr2
HypersensitivityCd14 , Il1b , Il1r1 , Il1r2 , Map2k6 , Tgfb1 , Tnf , Tnfrsf1a
Hypersensitivity, DelayedFgf2
Hypersensitivity, ImmediateEgfr
HypersplenismFas
HypertensionAkt1 , Akt2 , Atf2 , Cacna1c , Cacna2d1 , Casp3 , Cd14 , Dusp1 , Dusp5 , Egfr , Fgf2 , Fos , Hspa8 , Ikbkb , Il1b , Jun , Kras , Mapk8 , Ngf , Pdgfb , Pdgfra , Pdgfrb , Prkca , Prkcb , Rasgrp3 , Rela , Srf , Tgfb1 , Tgfb3 , Tnf , Tp53
Hypertension, PortalDusp1 , Il1b
Hypertension, PulmonaryEgfr , Fgf2 , Fgfr1 , Il1b , Myc , Nfatc2 , Pdgfa , Pdgfb , Rela , Tgfb1 , Tgfbr1 , Tgfbr2 , Tnf , Tp53
Hypertension, RenalHspa8 , Tnf
Hypertension, RenovascularPdgfa , Rela
Hypertensive EncephalopathyBdnf
Hypertensive NephropathyShc1
HypertrophyMapk1 , Mapk3
Hypertrophy, Left VentricularCacna1g , Dusp1 , Egfr , Mef2c , Myc , Nfatc4 , Ppp3ca , Ppp3cb , Ppp3r1 , Ppp5c , Prkca , Prkcb , Rac1 , Rasa1 , Rela , Shc1
Hypertrophy, Right VentricularAkt1 , Nfatc4 , Ppp3ca , Ppp3cb , Prkca , Tgfb1
HypochondroplasiaFgfr3
Hypoglossal Nerve InjuriesFgf2 , Fgfr1 , Il1r1 , Prkaca , Prkacb
HypoglycemiaAkt2 , Cacna1c , Il1b , Tnf
HypogonadismFgfr1
Hypogonadotropic Hypogonadism 19 with or without AnosmiaDusp6
Hypogonadotropic Hypogonadism 20 with or without AnosmiaFgf17
Hypogonadotropic Hypogonadism and Anosmia, Autosomal DominantFgfr1
Hypoinsulinemic Hypoglycemia with HemihypertrophyAkt2
Hypokalemic Periodic ParalysisCacna1s
Hypokalemic Periodic Paralysis, Type 1Cacna1s
HypolipoproteinemiasIl1b
Hypomagnesemia PrimaryEgf
Hypophosphatemia, FamilialFgf23
Hypophosphatemic Rickets, Autosomal DominantFgf23
HypospadiasFgf10 , Fgf8
HypotensionFgf1 , Il1a , Il1b , Tnf
HypothermiaFas , Faslg , Tnf
HypothyroidismBdnf , Ngf
Hypotonia-Cystinuria SyndromePpm1b
Hypoxia-Ischemia, BrainCasp3 , Daxx , Fas , Hspa1a , Il1b , Ntrk1 , Pdgfb , Ptpn5
Idiopathic Basal Ganglia Calcification 1Pdgfb
Idiopathic Dilation CardiomyopathyTnf
Idiopathic Hypogonadotropic HypogonadismFgfr1
Idiopathic Pulmonary FibrosisFas , Faslg , Ntrk2
Immune System DiseasesPrkcb
Immunodeficiency 15Ikbkb
Immunodeficiency without Anhidrotic Ectodermal DysplasiaIkbkg
Immunologic Deficiency SyndromesCacna1c
Impotence, VasculogenicTgfbr2
Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal DementiaEgf , Tnf
Incontinentia PigmentiIkbkg
Infarction, Middle Cerebral ArteryBdnf , Casp3 , Fgf21 , Fos , Ikbkb , Il1b , Ngf , Pdgfra , Pdgfrb , Tnf
InfectionTnf
Infectious MononucleosisFas , Faslg
Infertility, FemaleCacna2d2 , Mapk1 , Mapk3 , Tp53 , Tsc2
Infertility, MaleFas , Tp53
InflammationAkt1 , Bdnf , Chuk , Dusp10 , Egfr , Fgf2 , Il1a , Il1b , Ngf , Ntrk2 , Pdgfb , Pla2g4a , Tgfb1 , Tnf
Inflammatory Bowel Disease 11Casp3 , Gna12 , Il1b , Il1r2 , Rela , Tnf
Inflammatory Bowel DiseasesFgf23 , Hspa8 , Ikbkb , Pdgfb , Tnf
Influenza, HumanCd14 , Il1a , Il1b , Tnf , Tnfrsf1a
Insulin ResistanceAkt2 , Egfr , Ikbkb , Il1b , Nr4a1 , Pla2g1b , Prkcb , Rela , Shc1 , Tnf , Tnfrsf1a
InsulinomaTgfb1
Intellectual DisabilityBdnf , Cacna1g , Fgfr2 , Kras , Mapt , Mef2c , Nf1 , Ntf4 , Prkcg , Rps6ka3 , Tsc2
Intermittent ClaudicationCasp3
Intervertebral Disc DegenerationCrk , Ngf , Tgfb1
Intervertebral Disc DisplacementAkt1 , Bdnf , Tnf
Intestinal DiseasesCasp3 , Ddit3
Intestinal NeoplasmsPla2g2a , Prkca
Intestinal PolypsJun
Intestinal Pseudo-ObstructionFlna
Intestinal Reperfusion InjuryCd14
Intimal HyperplasiaPdgfrb
Intracranial AneurysmTnf
Intracranial HemorrhagesHspb1 , Tnf
Intrahepatic Cholestasis of PregnancyTnf
Invasive Pneumococcal Disease, Recurrent Isolated, 2Ikbkg
Invasive Pulmonary Asperg