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Pathways
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Ontology Browser
Term:
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway (PW:0000801)
Annotations: Rat: (60) Mouse: (61) Human: (61) Chinchilla: (58) Bonobo: (61) Dog: (60) Squirrel: (59) Pig: (60) Naked Mole-rat: (58) Green Monkey: (60)     Pathway Diagram Browser
Parent Terms Term With Siblings Child Terms
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway   
The pathway of beta adrenergic drug-target interactions and of the biochemical or physiological responses to drug. The beta-agonists are used to stimulate while the beta-blockers are used to inhibit the action of adrenergic beta receptors, as necessary. Adrenergic beta receptors are G-protein coupled receptors that in response to epinephrine or norepinephrine elicit various sympathetic responses important for proper cardiac function and in the case of beta2 receptor, smooth muscle relaxation and bronchodilation. Genetic variations can cause differences in the response of the organism to the drug.
View Interactive Diagram
adrenergic beta receptor agonist and beta-blocker pharmacokinetics pathway 

Synonyms
Related Synonyms: SMP:00296 ;   SMP:00297
Definition Sources: PMID:19874988

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