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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
angiotensin II signaling pathway via AT1 receptor   
angiotensin II signaling pathway via AT2 receptor   
Angiotensin II signaling through the angiotensin type 2 receptor (AT2) is less well understood and rather controversial. It appears to counteract AT1 receptor function and promote apoptosis. Alternatively, it may complement the effects of AT1 receptor with deleterious consequences in cardiac pathologies. AT2 receptor appears to function in a G-protein dependent as well as independent manner.

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Synonyms
Definition Sources: PMID:10977869, PMID:12734384, PMID:15158138, PMID:16286568

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