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Term:transforming growth factor-beta superfamily mediated signaling pathway
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Accession:PW:0000329 term browser browse the term     term annotations  view annotations
Definition:The TGF-beta superfamily of growth factors regulates a broad spectrum of processes such as angiogenesis, embryonic development, cell differentiation, proliferation, wound healing. Binding to two types of serine/threonine receptors and activation of Smad proteins is a common theme. However, ligand-receptor interaction and the identity of the activated Smad protein(s) appear to be member specific.
Synonyms:related_synonym: KEGG:04350;   TGF-beta signaling pathway - Homo sapiens (human);   TGF-beta signaling pathway - Mus musculus (mouse);   TGF-beta signaling pathway - Rattus norvegicus (rat);   TGF-beta superfamily mediated signaling pathway
Parent Terms Term With Siblings Child Terms
altered growth factor signaling pathway + 
angiopoietin signaling pathway 
epidermal growth factor/neuregulin signaling pathway + 
fibroblast growth factor signaling pathway + 
Gas6 - Axl signaling axis 
insulin-like growth factor signaling pathway + 
neurotrophic factor signaling pathway + 
platelet-derived growth factor signaling pathway 
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Stem Cell Factor signaling pathway
transforming growth factor-beta superfamily mediated signaling pathway + 
The TGF-beta superfamily of growth factors regulates a broad spectrum of processes such as angiogenesis, embryonic development, cell differentiation, proliferation, wound healing. Binding to two types of serine/threonine receptors and activation of Smad proteins is a common theme. However, ligand-receptor interaction and the identity of the activated Smad protein(s) appear to be member specific.
vascular endothelial growth factor signaling pathway + 
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