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Pathways
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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
dentatorubral-pallidoluysian atrophy pathway 
Huntington's disease pathway   
An autosomal dominant neurodegenerative disease manifesting in movement, cognitive and psychiatric disorders caused by the abnormal expansion of a polyglutamine (polyQ) stretch in the Huntingtin (HTT) protein. It mostly affects the caudate-putamen striatal neurons. Other areas are also affected and undergo a size reduction. HTT is thought to be involved in several cellular pathways. Its functions are overcome by the mutant protein mHTT.
View Interactive Diagram
Kennedy's disease pathway  
spinocerebellar ataxia pathway 

Synonyms
Exact Synonyms: HD pathway ;   Huntington disease pathway ;   Huntington's chorea pathway
Related Synonyms: KEGG:05016
Definition Sources: PMID:26938440

paths to the root