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Term:neurofibrillary tangles
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Accession:MP:0003214 term browser browse the term     term annotations  view annotations
Definition:dense intraneuronal accumulations of helical filaments (neurofilaments and microtubules) that assume twisted contorted patterns; found in subclasses of cells of the neocortex, hippocampus, brain stem, and diencephalon in individuals with Alzheimer disease and other tauopathies
Synonyms:related_synonym: neuritic plaques;   senile plaques
Parent Terms Term With Siblings Child Terms
abnormal brain copper level + 
abnormal brain development + 
abnormal brain interneuron morphology 
abnormal brain iron level 
abnormal brain size + 
abnormal brain vasculature morphology + 
abnormal brain ventricle/choroid plexus morphology + 
abnormal brain white matter morphology + 
abnormal brainstem morphology + 
abnormal forebrain morphology + 
abnormal hindbrain morphology + 
abnormal midbrain morphology + 
abnormal postnatal subventricular zone morphology + 
brain vacuoles 
cerebral amyloid angiopathy 
neurofibrillary tangles 
dense intraneuronal accumulations of helical filaments (neurofilaments and microtubules) that assume twisted contorted patterns; found in subclasses of cells of the neocortex, hippocampus, brain stem, and diencephalon in individuals with Alzheimer disease and other tauopathies
tau protein deposits 
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