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Term:GSI anchor biosynthetic process
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Accession:GO:0042082 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.
Synonyms:exact_synonym: GSI anchor anabolism;   GSI anchor biosynthesis;   GSI anchor formation;   GSI anchor synthesis
 broad_synonym: GPI/GSI anchor biosynthesis;   GPI/GSI anchor biosynthetic process
Parent Terms Term With Siblings Child Terms
C-terminal protein lipidation + 
ganglioside biosynthetic process + 
globoside biosynthetic process +
glycosylceramide biosynthetic process + 
GPI anchor biosynthetic process + 
GSI anchor biosynthetic process +
The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.
lactosylceramide biosynthetic process
mannosyl-inositol phosphorylceramide biosynthetic process
N-terminal protein lipidation + 
protein decanoylation +
protein myristoylation + 
protein octanoylation + 
protein palmitoleylation + 
protein palmitoylation + 
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