Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
calcium, potassium:sodium antiporter activity (GO:0008273)
Annotations: Rat: (5) Mouse: (5) Human: (5) Chinchilla: (5) Bonobo: (5) Dog: (5) Squirrel: (5) Pig: (5) Naked Mole-rat: (5) Green Monkey: (6)
Parent Terms Term With Siblings Child Terms
calcium, potassium:sodium antiporter activity  
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential  
potassium:proton antiporter activity  

Synonyms
Related Synonyms: potassium-dependent sodium/calcium exchanger
Xrefs: RHEA:69967 ;   Reactome:R-HSA-5625841 "Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+" ;   Reactome:R-HSA-5626270 "Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+" ;   Reactome:R-HSA-5626356 "Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+" ;   reactome:R-HSA-2514891 "SLC24A1 exchanges 4Na+ for Ca2+, K+" ;   reactome:R-HSA-425678 "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+" ;   reactome:R-HSA-5626316 "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+"
Definition Sources: TC:2.A.19.4.1

paths to the root