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Term:
superoxide dismutase activity
(GO:0004784)
Annotations:
Rat: (6)
Mouse: (6)
Human: (5)
Chinchilla: (5)
Bonobo: (6)
Dog: (5)
Squirrel: (4)
Pig: (5)
Naked Mole-rat: (5)
Green Monkey: (5)
Parent Terms
Term With Siblings
Child Terms
antioxidant activity
+
oxidoreductase activity, acting on superoxide radicals as acceptor
+
2-hydroxyisonicotinate dehydrogenase activity
citrazinate dehydrogenase activity
glutathione dehydrogenase (ascorbate) activity
glutathione-disulfide reductase (NADPH) activity
isonicotinate dehydrogenase activity
peroxidase activity
+
sulfiredoxin activity
superoxide dismutase activity
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
superoxide reductase activity
thioredoxin-disulfide reductase (NADPH) activity
Synonyms
Exact Synonyms:
superoxide:superoxide oxidoreductase activity
Narrow Synonyms:
Cu-Zn superoxide dismutase activity ; Mn, Fe superoxide dismutase ; copper, zinc superoxide dismutase activity ; ferrisuperoxide dismutase activity ; iron superoxide dismutase activity ; manganese superoxide dismutase activity ; nickel superoxide dismutase activity
Related Synonyms:
Cu,Zn-SOD ; Fe-SOD ; Mn-SOD ; SOD ; SOD-1 ; SOD-2 ; SOD-3 ; SOD-4 ; SODF ; SODS ; cuprein ; cytocuprein ; erythrocuprein ; hemocuprein ; hepatocuprein ; iron superoxide oxidoreductase ; manganese superoxide oxidoreductase ; nickel superoxide oxidoreductase ; superoxide dismutase I ; superoxide dismutase II ; zinc superoxide oxidoreductase
Alternate IDs:
GO:0004785 ; GO:0008382 ; GO:0008383 ; GO:0016954
Xrefs:
EC:1.15.1.1 ; MetaCyc:SUPEROX-DISMUT-RXN ; RHEA:20696 ; reactome:R-HSA-1222462 "SodB reduces superoxide to H2O2" ; reactome:R-HSA-1222469 "SodC reduces superoxide to H2O2" ; reactome:R-HSA-3299680 "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)" ; reactome:R-HSA-3299682 "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)" ; reactome:R-HSA-3299691 "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)" ; reactome:R-HSA-3777112 "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)"
Definition Sources:
EC:1.15.1.1, GOC:vw,
PMID:15064408