basal RNA polymerase II transcription machinery binding - Ontology Browser

Keyword

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Term:	basal RNA polymerase II transcription machinery binding	go back to main search page
Accession:	GO:0001099	browse the term view annotations
Definition:	Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.
Comment:	Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.

Parent Terms	Term With Siblings	Child Terms
basal transcription machinery binding +	bacterial-type RNA polymerase holo enzyme binding basal RNA polymerase II transcription machinery binding + Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.	RNA polymerase II basal transcription factor binding + RNA polymerase II core binding