spironolactone - Ontology Browser - Rat Genome Database

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Keyword

ONTOLOGY BROWSER

Term:	spironolactone	go back to main search page
Accession:	CHEBI:9241	browse the term view annotations
Definition:	A steroid lactone that has formula C24H32O4S.
Synonyms:	exact_synonym:	7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
	related_synonym:	C24H32O4S; InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1; InChIKey=LXMSZDCAJNLERA-ZHYRCANASA-N; [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]33CCC(=O)O3)[C@]1([H])[C@@H](CC1=CC(=O)CC[C@]21C)SC(C)=O; espironolactona; spironolactonum; spironolattone
	xref_casrn:	52-01-7
	xref:	Beilstein:57767 "Beilstein Registry Number"; ChemIDplus:52-01-7 "CAS Registry Number"; DrugBank:DB00421 "DrugBank"; KEGG COMPOUND:C07310 "KEGG COMPOUND"; KEGG DRUG:D00443 "KEGG DRUG"
	xref_mesh:	MESH:D013148
	xref:	Patent:US3013012 "Patent"

Parent Terms	Term With Siblings	Child Terms
3-oxo steroid + aldosterone antagonist + antihypertensive agent + diuretic + steroid lactone +	(25S)-dafachronic acid (2R,3S,2'R)-nadolol + (5alpha,22S,24R)-22-hydroxyergostan-3-one (S)-timolol (anhydrous) + (S)-timolol hemihydrate (S)-timolol maleate 11beta-hydroxyandrost-4-ene-3,17-dione 16alpha-hydroxyandrost-4-ene-3,17-dione 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one 17beta-hydroxy-5alpha-androstan-3-one 19-hydroxyandrost-4-ene-3,17-dione 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 20-hydroxy-3-oxopregn-4-en-21-al 3,17-dioxoandrost-4-en-19-al 3-dehydro-4-carboxyzymosterol 3-dehydro-4-methylzymosterol 3-dehydro-6-deoxoteasterone 3-dehydroecdysone 3-dehydroteasterone 3-oxo Delta(4)-steroid + 3-oxo Delta(5)-steroid + 3-oxo Delta(7)-steroid + 4,5-dihydrocortisone + 5alpha-androst-16-en-3-one 5alpha-campestan-3-one 5alpha-cholestan-3-one 5alpha-pregnane-3,20-dione 5beta-cholestan-3-one 5beta-pregnane-3,20-dione 6-methylprednisolone + 6-O-galloyl-beta-D-glucose 6beta-hydroxytestosterone 7alpha,12alpha,24-trihydroxy-5beta-cholestan-3-one + 7alpha,12alpha,24-trihydroxycholest-4-en-3-one + 7alpha,12alpha,26-trihydroxy-5beta-cholestan-3-one 7alpha,12alpha,26-trihydroxycholest-4-en-3-one 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 7alpha,12alpha-dihydroxycholest-4-en-3-one 7alpha,24-dihydroxy-5beta-cholestan-3-one + 7alpha,24-dihydroxycholest-4-en-3-one + 7alpha,26-dihydroxy-5beta-cholestan-3-one 7alpha,26-dihydroxycholest-4-en-3-one 7alpha-hydroxy-5beta-cholestan-3-one 7alpha-hydroxyandrost-4-ene-3,17-dione 7alpha-hydroxycholest-4-en-3-one 9,11alpha-epoxypregn-4-ene-3,20-dione 9alpha-hydroxyandrosta-1,4-diene-3,17-dione abrusoside A acebutolol acebutolol hydrochloride acetazolamide + ajugalactone alclometasone alclometasone dipropionate aldosterone + aldosterone hemiacetal alfuzosin + algestone + aliskiren + aliskiren fumarate alpha-methyl-L-dopa alpha-methyl-L-tyrosine alprenolol + amcinonide amiloride + amlodipine + amlodipine benzenesulfonate androst-4-ene-3,17-dione androsta-1,4-diene-3,17-dione androstane-3,17-dione + angiotensin-converting enzyme inhibitor + atenolol + azilsartan + azilsartan kamedoxomil azilsartan medoxomil bendroflumethiazide + benzthiazide bepridil + betamethasone + betamethasone valerate betaxolol + betaxolol hydrochloride + bethanidine + bethanidine sulfate bevantolol + bevantolol hydrochloride + bimatoprost bisoprolol + boldenone bosentan + bretylium + bretylium tosylate brimonidine + budesonide bufanolide + bumetanide calcitriol 26,23-lactone campest-4-en-3-one candesartan captopril + cardanolide + cardenolide + carmoxirole carmoxirole hydrochloride carteolol carteolol hydrochloride carvedilol chlormerodrin + chlorothiazide cholest-4-en-3-one cilnidipine clonidine + convallatoxin corilagin corticosterone + cortisol + cortisone + cyasterone cyclothiazide cyproterone + cyproterone acetate debrisoquin + Delta(1)-dihydrotestosterone deoxycortisol + dexamethasone + diazoxide diltiazem + diltiazem hydrochloride dorzolamide + dorzolamide hydrochloride doxazosin + drospirenone dydrogesterone elaeodendroside B elaeodendroside F elaeodendroside G elaeodendroside T elaeodendroside V elaeodendroside W enalapril + enalapril maleate enalaprilat (anhydrous) + enalaprilat dihydrate eplerenone eprosartan + eprosartan methanesulfonate ethacrynic acid ethoxzolamide etonogestrel felodipine fenoldopam finasteride fludrocortisone flumethasone + flumethasone pivalate fluprostenol + fosinopril fosinopril sodium fosinoprilat + furosemide grayanotoxin I guanadrel guanadrel sulfate guanethidine + guanethidine monosulfate + guanethidine sulfate halosterol A hydralazine + hydralazine hydrochloride hydrocortamate + hydrocortisone caproate indapamide irbesartan isoamyl nitrite isopropyl unoprostone kaempferide ketanserin labetalol latanoprost latanoprost free acid + LD-norgestrel lisinopril dihydrate lofexidine losartan loteprednol + loteprednol etabonate medroxyprogesterone + megestrol + metholone + metipranolol metipranolol hydrochloride metolazone mifepristone minoxidil mometasone + nadolol nandrolone + nebivolol nimodipine norethisterone norgestrel + olmesartan osmotic diuretic + oxandrolone palmitoyl ethanolamide pentolinium tartrate pindolol + potassium citrate (anhydrous) + potassium citrate monohydrate pratosartan prazosin + prednisolone + prednisone + pregna-4,9(11)-diene-3,20-dione propranolol + rescinnamine reserpine sarmentologenin + scillirosidin + spironolactone A steroid lactone that has formula C24H32O4S. telmisartan terazosin + testololactone testosterone + tixocortol + tolazoline travoprost treprostinil + trimethaphan + unoprostone + valsartan vincamine zymosterol intermediate 2

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