| Term: | geldanamycin |
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| Accession: | CHEBI:5292
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| Definition: | A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. it is an ansamycin antibiotic and thus shows antimicrobial activity against many gram-positive and some gram-negative bacteria. |
| Synonyms: | exact_synonym: | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate |
| | related_synonym: | C29H40N2O9; CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\\C(C)=C\\C=C/[C@H](OC)[C@@H](OC(N)=O)\\C(C)=C\\[C@H](C)[C@H]1O)C2=O; InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1; InChIKey=QTQAWLPCGQOSGP-KSRBKZBZSA-N |
| | alt_id: | CHEBI:42670 |
| | xref_casrn: | 30562-34-6 |
| | xref: | ChEMBL:125906 "ChEMBL COMPOUND"; ChemIDplus:30562-34-6 "CAS Registry Number"; CiteXplore:21983172 "PubMed citation"; CiteXplore:21985437 "PubMed citation"; CiteXplore:22050565 "PubMed citation"; CiteXplore:22136518 "PubMed citation"; CiteXplore:22138446 "PubMed citation"; CiteXplore:22215907 "PubMed citation"; CiteXplore:22277058 "PubMed citation"; CiteXplore:22361388 "PubMed citation"; KEGG COMPOUND:C11222 "KEGG COMPOUND" |
| | xref_mesh: | MESH:C001277 |
| | xref: | PDBeChem:GDM "PDBeChem"; Wikipedia:Geldanamycin "Wikipedia" |
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