ONTOLOGY BROWSER
| Term: | imatinib |
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| Accession: | CHEBI:45783
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| Definition: | A N-methylpiperazine that has formula C29H31N7O. |
| Synonyms: | related_synonym: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE; 4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide; C29H31N7O; CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1; InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34); InChIKey=KTUFNOKKBVMGRW-UHFFFAOYSA-N; STI 571; alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide |
| | alt_id: | CHEBI:305376; CHEBI:38918; CHEBI:45781 |
| | xref_casrn: | 152459-95-5 |
| | xref: | Beilstein:7671333 "Beilstein Registry Number"; ChEMBL:188797 "ChEMBL COMPOUND"; ChEMBL:305376 "ChEMBL COMPOUND"; ChemIDplus:152459-95-5 "CAS Registry Number"; CiteXplore:17457302 "PubMed citation"; CiteXplore:18407734 "PubMed citation"; DrugBank:DB00619 "DrugBank" |
| | xref_mesh: | MESH:C097613 |
| | xref: | PDBeChem:STI "PDBeChem"; Patent:EP564409 "Patent"; Patent:US5521184 "Patent"; Wikipedia:Imatinib "Wikipedia" |
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| Parent Terms |
Term With Siblings |
Child Terms |
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(+)-aplysinillin
(+)-dexrazoxane +
(+)-dihydromyricetin
(+)-syringaresinol +
(-)-annonaine +
(-)-beta-elemene
(-)-demecolcine
(-)-epigallocatechin 3-gallate
(-)-marinopyrrole A
(2->6)-beta-D-fructan
(22E,24R)-5alpha,8alpha-epidioxyergosta-6,9,22-triene-3beta-ol-3-O-beta-D-glucopyranoside
(2S)-(-)-kurarinone +
(2S)-2'-hydroxy-7,8,3',4',5'-pentamethoxyflavan
(2S)-2'-methoxykurarinone
(2S)-5,7-dimethoxy-8-(2S-hydroxy-3-methyl-3-butenyl)-3',4'-methylenedioxyflavanone
(2S)-5,7-dimethoxy-8-formylflavanone
(2S,4S,5S)-5-[((2S)-2-\{(3R)-3-benzyl-4-[(4-methylpiperazin-1-yl)carbonyl]-2-oxopiperazin-1-yl\}hexanoyl)amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-isopropylhexanamide
(2Z,3Z)-bis\{amino[(2-aminophenyl)sulfanyl]methylidene\}butanedinitrile
(3E)-N-(2,6-diethylphenyl)-3-\{[4-(4-methylpiperazin-1-yl)benzoyl]imino\}pyrrolo[3,4-c]pyrazole-5(3H)-carboxamide
(6S)-5-formyltetrahydrofolic acid
1-(3-(2,4-dimethylthiazol-5-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl)-3-(4-methylpiperazin-1-yl)urea
1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone
1-deoxysphinganine
1-methyltryptophan
1-NA-PP1
1-NM-PP1
1-O-(alpha-D-galactopyranosyl)-N-hexacosanoylphytosphingosine
10-hydroxycanthin-6-one
12-deacetoxy-21-acetoxyscalarin
12-O-acetyl-16-O-deacetyl-16-epi-scalarobutenolide
13,14-dihydro-Delta(12)-prostaglandin J2
15-O-deacetylnimbolidin B
16,23-epoxy-5beta-cholestane triglycoside
16-O-deacetyl-16-epi-scalarolbutenolide
1R,4S,6R-1,4-endoperoxy-bisabola-2,10-diene
1S,4R,6R-1,4-endoperoxy-bisabola-2,10-diene
2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone
2'-(3-iodo-4-methoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2'-(3-iodophenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2'-(3-methyl-4-dimethylaminophenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2'-(4-dimethylaminophenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2'-(4-hydroxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole
2,6-dimethylphenyl 2-\{3,5-dimethoxy-4-[3-(4-methylpiperazin-1-yl)propoxy]phenylamino\}pyrimidin-4-yl-(2,4-dimethoxyphenyl)carbamate
2-(2,4-dihydroxy-5-prenylphenyl)-5,6-methylenedioxybenzofuran
2-fluoroadenine +
2-methoxy-17beta-estradiol +
20(R),22(xi),24(S)-dammar-25(26)-ene-3beta,6alpha,12beta,20,22,24-hexanol
20-epi-bryonolic acid
3',4',5-trihydroxy-3,6,7-trimethoxyflavone
3',4',7-trihydroxyisoflavone
3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin
3,3'-diindolylmethane
3,5-dihydroxy-2-(1'-oxo-3'-hexadecenyl)-2-cyclohexene-1-one
3-\{6-[5-(4-methylpiperazin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl]-1H-benzimidazol-2-yl\}phenol
3-acetamino-6-isobutyl-2,5-dioxopiperazine
3-beta-O-(E)-coumaroyl-D:C-friedooleana-7,9(11)-dien-29-oic acid
3-epi-heliangin
3beta,12-dihydroxy-13-methyl-5,8,11,13-podocarpatetraene-7-one
3beta-O-\{alpha-L-Rhap-(1->2)-beta-D-Glcp-(1->4)-[beta-D-Glcp-(1->2)]-alpha-L-Arap\}primulagenin A
4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin
4',5,7-trihydroxy-3'-methoxyflavone +
4'-epidoxorubicin
4,5-dianilinophthalimide
4-(4-methylpiperazin-1-yl)-N-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide
4-(\{[(4-methylpiperazin-1-yl)amino]carbothioyl\}amino)benzenesulfonamide
4-[(4-methylpiperazin-1-yl)methyl]-N-\{3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl\}benzamide
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid
4-hydroperoxycyclophosphamide
4-hydroxyphenyl retinamide
4-methyl-5-\{(2E)-2-[(4-morpholin-4-ylphenyl)imino]-2,5-dihydropyrimidin-4-yl\}-1,3-thiazol-2-amine
4-methyl-5-pentylbenzene-1,3-diol
4-methylaeruginoic acid
4-methylpiperazine-1-carbaldehyde
4-phenylbutyric acid
5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin
5-aminolevulinic acid +
5-bromo-2'-deoxyuridine
5-bromo-8-methoxy-1-methyl-beta-carboline
5-bromouracil
5-fluoro-2'-deoxyuridine
5-fluorouracil
5-hydroxy-2-(1'-hydroxyethyl)naphtho[2,3-b]furan-4,9-dione
5-hydroxy-7-prop-2-en-(E)-ylidene-7,7a-dihydro- 2H-cyclopenta[b]pyran-6-one
5-hydroxy-7-prop-2-en-(Z)-ylidene-7,7a-dihydro- 2H-cyclopenta[b]pyran-6-one
5-methylcytosine +
5-O-ethyl embelin
5-O-methyl embelin
5alpha,8alpha-epidioxycholest-6-en-3beta-ol
5alpha,8alpha-epidioxysterol
6,7-dimethoxy-4-\{8-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydroisoquinolin-2-(1H)-yl\}quinazoline
6-(4-\{(1S,2S)-2-amino-1-[(dimethylamino)carbonyl]-3-[(3S)-3-fluoropyrrolidin-1-yl]-3-oxopropyl\}phenyl)-1H-[1,2,4]triazolo[1,5-a]pyridin-4-ium
6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)ethyl]-9H-purine-2-carbonitrile
6-azauridine
6-hydroxypaclitaxel
7,8-dihydroxyflavanone
7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-4E-heptene-3-one
7-(4''-hydroxy-3''-methoxyphenyl)-5-methoxy-1-phenyl-3-heptanone
7alpha-hydroperoxy manool
8-azaguanine
8-hydroxy-2-(1'-hydroxyethyl)naphtho-[2,3-b]-furan-4,9-dione
9(11)-dehydroaxinysterol
9-cis-retinoic acid +
9-cyclopentyl-6-\{2-[3-(4-methylpiperazin-1-yl)propoxy]phenylamino\}-9H-purine-2-carbonitrile
9-deacetoxyfumigaclavine C
9-hydroxy hedychenone
9-hydroxycanthin-6-one
abarelix
abiraterone +
abiraterone acetate
abyssinone A
abyssinone C
abyssinone D
acronycine
aculeatol E
acumitin
afatinib
afimoxifene
agathisflavone
ageladine A
agigenin +
aklavinone
albizoside A
albizoside B
albizoside C
alfuzosin +
all-trans-retinoic acid +
allanxanthone C
alogliptin
alvaradoin E
alvaradoin F
alvaradoin G
alvaradoin H
alvaradoin I
alvaradoin J
alvaradoin K
alvaradoin L
alvaradoin M
alvaradoin N
amidopyrimidine +
aminocyclopyrachlor +
aminoglutethimide +
aminopyrimidine +
amocarzine
amomol A
anastrozole
andrographolide
ansamitocin P3
antroquinonol
aphidicolin
apigenin +
aplysinoplide A
aplysinoplide B
aplysinoplide C
apratoxin A
apratoxin D
apratoxin E
ardisianoside A
ardisianoside B
ardisianoside C
ardisianoside D
ardisianoside E
ardisiphenol A
ardisiphenol B
ardisiphenol C
arenamide A
arenamide B
argpyrimidine
artocarpin
artochamin C
artoindonesianin E1
artoindonesianin P
aryloxypyrimidine +
asperfuranone
aspergillide A
aspergillide B
aspergillide C
asprellic acid A
asprellic acid C
avanafil
axitinib
azathioprine
azelaic acid
BE-23372M
BE-54238A
BE-54238B
belinostat
benzamido group
beta-elemene +
beta-lapachone
beta-thujaplicin
betulin +
betulinic acid +
bexarotene
BF 4
BF 5
BF 6
BGJ-398
BGT226
BGT226 free base
bicalutamide
bielschowskysin
bistratamide E
bistratamide F
bistratamide G
bistratamide H
bistratamide I
bistratamide J
BKM120
bleomycin A2
bleomycin B2
BML-210
bortezomib
bosentan +
bosutinib +
bosutinib hydrate
bowdichione
brasilicardin A
brasiliquinone A
brasiliquinone B
brasiliquinone C
brasixanthone B
brasixanthone C
brasixanthone D
brevipolide A
brevipolide B
bromophycolide A
bufalin
buspirone +
busulfan
butein
cabazitaxel
cabergoline
cabozantinib +
cabozantinib malate
cadiyenol
calcitriol +
calicheamicin gamma1(I)
callophycoic acid A
callophycoic acid C
callophycoic acid D
callophycoic acid E
callophycoic acid F
callophycoic acid G
callophycoic acid H
callophycol A
callophycol B
calotropone
camptothecin
canertinib
capecitabine
capilliposide B
carboplatin
cardivin A
cardivin B
cardivin C
cardivin D
carfilzomib
carmustine
carnosic acid
caseamemebrol A
caseamemebrol B
caseanigrescen A
caseanigrescen B
caseanigrescen C
caseanigrescen D
caudatin-3-O-beta-cymaropyranoside
celastrol
celebixanthone +
cembra-2,7,11-triene-4,6-diol
cetrorelix +
cetrorelix acetate
CH5424802
chlorotrianisene
cidofovir anhydrous +
cidofovir dihydrate
ciglitazone
ciliatamide B
cisplatin
cladoniamide G
cladribine
clavulone II
clionastatin A
clionastatin B
clodronic acid
clofarabine
clozapine
colpol
cordycepin triphosphate
cordyol C
corynoline
costunolide
crassumolide A
cratoxyarborenone A
cratoxyarborenone B
cratoxyarborenone C
cratoxyarborenone D
cratoxyarborenone E
cratoxyarborenone F
crizotinib
cudratricusxanthone A
curcumin +
cyclodepsipeptide 2
cyclophosphamide +
cyclophosphamide hydrate
cystodytin D +
cystodytin E +
cystodytin F
cystodytin G
cystodytin H
cystodytin I
cystothiazole A
cytarabine
cytotrienin A
dacarbazine
dactolisib
daidzein +
dasatinib (anhydrous) +
dasatinib monohydrate
DCC-2036
decursinol
dehydrocostus lactone
delphinidin +
demethoxycurcumin
dexamethasone +
dexrazoxane hydrochloride
dianversicoside A
dianversicoside B
dianversicoside C
dianversicoside D
dianversicoside E
dianversicoside F
dianversicoside G
diarsenic trioxide
diazinon
dicerandrol A
dicerandrol B
dicerandrol C
diethylcarbamazine
diethylstilbestrol +
dinochrome A
diosmetin
diuvaretin
docetaxel anhydrous +
docetaxel trihydrate
doxazosin +
dromostanolone propionate
E-3810
E-3810 free base
elaeodendroside B
elaeodendroside F
elaeodendroside G
elaeodendroside T
elaeodendroside U
elaeodendroside W
elephantin
elongatol A
elongatol E
emarginatine B
emarginatine F
embelin +
emodin +
englerin A
enrofloxacin
ent-kaur-16-en-19-oic acid
enzalutamide
epothilone A
ergosterol peroxide
eribulin
eribulin mesylate
erlotinib +
erlotinib hydrochloride
erybraedin A
esculeoside A
esperamicin A1
estramustine +
estrone +
etidronic acid
etoposide
eugeniin
eupaheliangolide A
eupatilin
euphornin L
eurysterol A
eurysterol A sulfonic acid
eurysterol B
eurysterol B sulfonic acid
everolimus
exemestane
F390B
F390C
FD-211
flavokawain B
fluacrypyrim
fludarabine phosphate
fluoxymesterone
flutamide
formycin A +
FR901463
FR901464
FR901465
fulvestrant
fuzanin D
gaudichaudiic acid F
gaudichaudiic acid G
gaudichaudiic acid H
gaudichaudiic acid I
gedunin
gefitinib +
geldanamycin +
gelomulide K
gelomulide M
gemcitabine +
gemcitabine hydrochloride
genistein +
gilvusmycin
ginkgetin
glionitrin A
globostellatic acid A
globostellatic acid B
globostellatic acid C
globostellatic acid D
glochierioside A
glochierioside B
gnidilatimonoein
granaticin
grassypeptolide
GSK1059615
gummiferaoside A
gummiferaoside B
gummiferaoside C
hadacidin
HC toxin
hedychilactone D
heliangin
herbimycin
hesperetin +
hinokiflavone
histrelin +
histrelin acetate
hydramethylnon +
hydroxypyrimidine +
hydroxytyrosol +
hyperxanthone C
hyperxanthone E
hypocrellin D
ifosfamide
igalan
imatinib + A N-methylpiperazine that has formula C29H31N7O.
imatinib methanesulfonate
imiquimod
indapamide
ingenol mebutate
isariotin F
isochamuvaritin
isoiguesterin
isoorientin +
isotretinoin
isowigtheone hydrate
ixabepilone
ixerochinolide
jaceosidin
Janus kinase inhibitor +
jaspamide
jaspamide B
jaspamide C
jaspamide D
jaspamide E
jaspamide F
jaspamide G
jaspamide H
jaspamide J
jaspamide K
jaspamide L
jaspamide M
jaspamide N
jaspamide O
jaspamide P
jerantinine A +
jerantinine B
jerantinine C +
jerantinine D
jerantinine E
jerantinine F
jineol
juglanin A
juglanin B
kadlongilactone A
kadlongilactone B
kaempferol 7-O-(2,3-di-E-p-coumaroyl-alpha-L-rhamnopyranoside)
kaempferol 7-O-(2-E-p-coumaroyl-alpha-L-rhamnopyranoside)
kansuiphorin A
kansuiphorin B
kidjoranin-3-O-alpha-diginopyranosyl-(1->4)-beta-cymaropyranoside
kidjoranin-3-O-beta-digitoxopyranoside
kievitone +
kitastatin 1
knipholone +
koshikamide A2
kweichowenol B
lapatinib
laurebiphenyl
leachianone A
leflunomide
lenalidomide
letrozole
leucospiroside A
leuprolide +
leuprolide acetate
linkable imatinib analogue
liriodenine
longicalycinin A
lovastatin
lucanthone +
lucialdehyde B
lucialdehyde C
lucidenic acid N
luteolin +
marimastat
marineosin A
marineosin B
masitinib
maslinic acid +
mechlorethamine hydrochloride
megestrol +
melphalan
mercaptopurine +
metachromin S
metachromin T
metholone +
methotrexate
methoxsalen +
methyl (indol-3-yl)acetate
methyl 5-aminolevulinate +
methyl 5-aminolevulinate hydrochloride
methylpiperazinoforskolin
methylselenol
methyltestosterone
miboplatin
midostaurin
migrastatin
minquartynoic acid
mithramycin
mitoxantrone +
mitoxantrone dihydrochloride
moromycin A
moromycin B
MTIC
mycophenolic acid +
myo-inositol hexakisphosphate
myricetin +
N(6)-(Delta(2)-isopentenyl)adenosine +
N-(4-\{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide
N-[(1S)-3-\{[(benzyloxy)amino]sulfonyl\}-1-(2-phenylethyl)propyl]-N-[(4-methylpiperazin-1-yl)carbonyl]-L-phenylalaninamide
N-[(3E)-5-[(2R)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5H)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide
N-[(4-methylpiperazin-1-yl)carbonyl]-L-phenylalanin-(N-\{(1S)-3-phenyl-1-[2-(benzenesulfonyl)ethyl]propyl\})amide
N-[2-(2-aminoethoxy)ethyl]-4-(2-hydroxy-4-phenylcyclohexyl)benzamide
N-\{4-[4-(4-methylpiperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)pyrimidin-2-ylsulfanyl]phenyl\}cyclopropanecarboxamide
N-\{5-[4-(4-methylpiperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl\}nicotinamide
N-benzoyl-1-methylpyridin-4(1H)-imine
N-butyrylbenzamide
N-desmethylenzalutamide
N-hydroxyguanidine
naringin
nelarabine
neobavaisoflavone +
neocarzinostatin chromophore
neohesperidin
neratinib
nidulalin A
nilotinib
nilutamide
nitropyrimidine +
nitrosopyrimidine +
nitrososulfadiazine
NK154183A
NK154183B
nogalamycin
Nutlin +
O-(2-aminoethyl)-L-serine
olanzapine
omacetaxine mepesuccinate
orbiculin A
orbiculin E
orbiculin F
orbiculin G +
oroxylin A +
oxaliplatin +
paclitaxel +
palau'amide
pasireotide
pasireotide aspartate
pazopanib
pazopanib hydrochloride
PD173074
PD173955 +
pemetrexed
pemetrexed disodium +
pemetrexed disodium heptahydrate
perazine
perillic acid +
phenethyl isothiocyanate
phomacin A
phomacin B
phomacin C
pibenzimol +
pirinixic acid
pleosporone
plumbagin
PM-94128
podophyllotoxin +
polyketomycin
pomalidomide
porfimer
porfimer sodium
PP121
pralatrexate
prednisone +
procarbazine
procarbazine hydrochloride
prochlorperazine +
procyanidin B4
pterostilbene
puromycin +
pyrimidine
pyrimidine N-oxide +
pyrimidine nucleobase +
pyrimidine nucleoside +
pyrimidine nucleotide +
pyrimidine-2-thiol
pyrimidinecarboxamide +
pyrimidinecarboxylate anion +
pyrimidinecarboxylate ester +
pyrimidinedicarboxylic acid +
pyrimidinemonocarboxylic acid +
pyrimidinethione +
pyrimidinimine +
pyrimidinium salt +
pyrimidone +
pyrimidylpyridine +
quercetin +
radicicol
regorafenib +
regorafenib hydrate
retaspimycin
retaspimycin hydrochloride
reversine
rhizoxin
rifampicin
robustaflavone +
robustaflavone 7,4',7''-trimethyl ether
romidepsin
rosuvastatin
rotenone
ruxolitinib +
ruxolitinib phosphate
scutellarin
scytalidamide A
scytalidamide B
Se-methyl-L-selenocysteine +
Se-methylselenocysteine +
silver(1+) sulfadiazinate
silymarin
sirolimus +
sodium globostellatate B
sodium globostellatate A
sodium globostellatate C
sodium globostellatate D
sodium stibogluconate
sorafenib +
streptokordin
streptonigrin
streptozocin
sulfadiazine
sulfadiazine hydroxylamine
sulfadimethoxine
sulfadoxine
sulfamerazine
sulfamethazine
sulfamethoxydiazine
sulfisomidine
sulindac +
sunitinib +
surfactin
surfactin A +
surfactin B +
surfactin C +
surfactin D +
swainsonine
tabersonine +
tamibarotene
tamoxifen +
tamsulosin +
tanespimycin
tangeretin
temozolomide
tephrosin +
terazosin +
teriflunomide
terrequinone A
thiethylperazine +
thioproperazine
thiostrepton
tioguanine
TMC-135A
TMC-135B
TMC-1A
TMC-1B
TMC-1C
TMC-1D
TMC-86A
TMC-86B
TMC-95A
TMC-95B
TMC-95C
TMC-95D
TMC-96
topopyrone A
topopyrone B
topopyrone C
topopyrone D
topotecan
toremifene
trans-2-hydroxyisoxypropyl-3-hydroxy-7-isopentene-2,3-dihydrobenzofuran-5-carboxylic acid
tricetin +
trichodermin
trierixin
trifluoperazine +
trilostane
triptorelin
troglitazone
tubercidin +
ubiquinol-8
UCS1025 A
urdamycin A
vandetanib +
vemurafenib
verteporfin
vindesine +
vindesine sulfate
vinorelbine +
vinorelbine D-tartrate
vinorelbine L-tartrate
vismodegib
vitexin +
voriconazole
wedelolactone
wogonin +
WZ4002
XL147
XL765
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