ONTOLOGY BROWSER
| Term: | carvedilol |
|
| Accession: | CHEBI:3441
|
 browse the term
 view annotations
|
| Definition: | A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure. |
| Synonyms: | exact_synonym: | 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol |
| | related_synonym: | (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol; C24H26N2O4; COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12; InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3; InChIKey=OGHNVEJMJSYVRP-UHFFFAOYSA-N; SKF 105517; carvedilolum |
| | xref_casrn: | 72956-09-3 |
| | xref: | Beilstein:1514452 "Beilstein Registry Number"; ChEMBL:136662 "ChEMBL COMPOUND"; ChemIDplus:72956-09-3 "CAS Registry Number"; CiteXplore:11389884 "PubMed citation"; CiteXplore:15184840 "PubMed citation"; CiteXplore:17383596 "PubMed citation"; CiteXplore:18992766 "PubMed citation"; DrugBank:DB01136 "DrugBank"; HMDB:HMDB15267 "HMDB"; KEGG COMPOUND:72956-09-3 "CAS Registry Number"; KEGG COMPOUND:C06875 "KEGG COMPOUND"; KEGG DRUG:D00255 "KEGG DRUG" |
| | xref_mesh: | MESH:C043211 |
| | xref: | Patent:DE2815926 "Patent"; Patent:US4503067 "Patent"; Reaxys:1514452 "Reaxys Registry Number"; Wikipedia:Carvedilol "Wikipedia" |
|
|
| Parent Terms |
Term With Siblings |
Child Terms |
|
|
(+)-aplysinillin
(+)-calanolide A
(+)-dexrazoxane +
(+)-phytocassane A
(+)-phytocassane B
(+)-phytocassane C
(+)-phytocassane D
(+)-phytocassane E
(+)-thujan-3-ol
(-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin
(-)-calanolide B
(-)-cubebin
(-)-demecolcine
(-)-threo-isodihomocitric acid
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin
(2R,3S,2'R)-nadolol +
(2R,3S,2'S)-nadolol +
(2S)-2-hydroxy-3,4-diketopentyl phosphate
(2S)-5,7-dimethoxy-8-(2S-hydroxy-3-methyl-3-butenyl)-3',4'-methylenedioxyflavanone
(2S,3R,2'R)-nadolol +
(2S,3R,2'S)-nadolol +
(3R,4S,1'R)-3-(1'-hydroxyethyl)-4-methyldihydrofuran-2(3H)-one
(R)-adrenaline +
(S)-timolol (anhydrous) +
(S)-timolol hemihydrate
(S)-timolol maleate
1,1,1,3,3,3-hexafluoropropan-2-ol
1,2-bis(4-hydroxyphenyl)-2-propanol
1,2-bis(4-hydroxyphenyl)propan-2-ol
1,3-dichloro-2-propanol
1-[(1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl]thymine
1-[(1S,3S,4R,5S)-3-hydroxy-4-(hydroxymethyl)bicyclo[3.1.0]hexan-1-yl]thymine
1-[3-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]ethanol
1-[4-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]ethanol
11-oxo-ent-cassa-12,15-dien-2alpha,3alpha-diol
11-oxo-ent-cassa-12,15-dien-3alpha-ol
11alpha-hydroxy-beta-amyrin
11alpha-hydroxy-ent-cassa-12,15-diene
12-deacetoxy-21-acetoxyscalarin
12-O-acetyl-16-O-deacetyl-16-epi-scalarobutenolide
15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid
15-O-deacetylnimbolidin B
16-O-deacetyl-16-epi-scalarolbutenolide
16alpha-hydroxygypsogenic acid +
1alpha-acetoxy-2alpha-hydroxy-6beta,9beta,15-tribenzoyloxy-beta-dihydroagarofuran
2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] +
2,6-dihydroxypseudooxynicotine
2-(4-hydroxyphenyl)ethanol +
2-(hydroxymethyl)-4-(1-hydroxy-2-\{[6-(4-phenylbutoxy)hexyl]amino\}ethyl)phenol +
2-hydroxy-1-phenyl-1-propanone
2-hydroxyoctadecanal
2-hydroxypropylphosphonic acid +
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
21beta-hydroxyolean-12-en-3-one
2alpha-acetoxy-1alpha-hydroxy-6beta,9beta,15-tribenzoyloxy-beta-dihydroagarofuran
3,3,5-trimethylcyclohexanol +
3,4-dihydro-4-hydroxyphenylpyruvic acid
3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvic acid
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol
3-\{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl\}propanoic acid +
3-hydroxy-alpha-ionone
3-O-trans-p-coumaroyl actinidic acid
3-quinuclidinol +
3beta,12-dihydroxy-13-methyl-5,8,11,13-podocarpatetraene-7-one
4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin
4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
4-hydroxydebrisoquin
4beta,14-dihydroxy-6alpha,7beta-H-1(10)-cadinene
5-[(1-phenylcyclohexyl)amino]pentanoic acid
5-hydroxy-2-(1'-hydroxyethyl)naphtho[2,3-b]furan-4,9-dione
5-hydroxyectoine
5-hydroxyzerumbone
6-ethyl-5-[9-(3-methoxypropyl)-9H-carbazol-2-yl]pyrimidine-2,4-diamine
6-hydroxypseudooxynicotine
6-O-galloyl-beta-D-glucose
7,2'-dihydroxy-4'-methoxyisoflavanol +
7-\{[2-(\{1-[(1Z)-ethanimidoyl]piperidin-4-yl\}oxy)-9H-carbazol-9-yl]methyl\}naphthalene-2-carboximidamide
7-epiclusianone
7beta-hydroxytaxusin
8-hydroxy-2-(1'-hydroxyethyl)naphtho-[2,3-b]-furan-4,9-dione
8-hydroxy-alpha-humulene
9(11)-dehydroaxinysterol
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol +
acebutolol
acebutolol hydrochloride
acetylcholine +
adenosine +
albuterol +
alfuzosin +
aliskiren +
aliskiren fumarate
alismorientol A
Aloe C-glucosylchromone
alpha-amyrin
alpha-methyl-L-dopa
alpha-methyl-L-tyrosine
alpha-seco-amyrin
alprenolol +
alvespimycin
amineptine +
amlodipine +
amlodipine benzenesulfonate
amomol A
anagalligenin A +
anagrelide +
andrographolide
angiotensin-converting enzyme inhibitor +
anti-arrhythmia drug +
antiatherogenic agent +
antroquinonol
aplysinoplide A
aplysinoplide B
arabidiol
ardisianoside A
ardisianoside B
ardisianoside C
ardisianoside D
ardisianoside E
argipressin
AS-186a +
AS-186d
asenapine
asenapine maleate
asperfuranone
aspergillide A
aspergillide B
aspergillide C
atenolol +
australifungin
avanafil
avermitilol
azilsartan +
azilsartan kamedoxomil
azilsartan medoxomil
bacillaene
bamethan +
baruol
BE-54238A
BE-54238B
bendroflumethiazide +
benzonatate
benzthiazide
bepridil +
beta-amyrin +
beta-seco-amyrin
betahistine
betaxolol +
betaxolol hydrochloride +
bethanidine +
bethanidine sulfate
bevantolol +
bevantolol hydrochloride +
bidenlignaside A
bidenlignaside B
bimatoprost
bisoprolol +
bitolterol +
bitolterol mesylate +
bosentan +
brasixanthone D
bretylium +
bretylium tosylate
brimonidine +
bucladesine
butan-2-ol +
cadiyenol
CAF-603
camelliol C
candelalide B
candesartan
capilliposide B
captopril +
carbazole +
cardiotonic drug +
cardivin A
cardivin B
cardivin C
cardivin D
carmoxirole
carmoxirole hydrochloride
carprofen +
carteolol
carteolol hydrochloride
carvedilol A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
caseamemebrol A
caseamemebrol B
caseanigrescen A
caseanigrescen B
caseanigrescen C
caseanigrescen D
caulophine
celasdin B
ceratamine A
CGP 78608
chanoclavine-I +
chanoclavine-I aldehyde
chlorothiazide
cilnidipine
cilostazol
cimifoetiside A
cimifoetiside B
cinacalcet +
cinnamaldehyde
clenbuterol +
clonidine +
clopenthixol +
colossolactone VIII
conduritol +
conferol A
conferol B
convallatoxin
corilagin
cortistatin A +
cortistatin B +
cortistatin C +
cortistatin D
corynoline
crambescidin 800
crassifogenin C
crassumolide A
CT2108A
CT2108B
cyclandelate
cyclohexanol
cyclothiazide
cystodytin D +
cystodytin E +
cytotrienin A
dammarenediol-II
dapiprazole
dasatinib (anhydrous) +
debrisoquin +
decursinol
delta-amyrin
desacetylpyramidaglain D
desipramine +
dexrazoxane hydrochloride
diazoxide
dihydroergocristine +
dihydroergocristine mesylate +
dihydrophaseic acid
diltiazem +
diltiazem hydrochloride
dinochrome A
dipyridamole
dorzolamide +
dorzolamide hydrochloride
doxazosin +
dyphylline +
dysidine
enalapril +
enalapril maleate
enalaprilat (anhydrous) +
enalaprilat dihydrate
ent-cassa-12,15-dien-3alpha-ol
entecavir (anhydrous) +
epi-cochlioquinone A
epi-dihydrophaseic acid
eplerenone
eprosartan +
eprosartan methanesulfonate
ergoloid mesylate
erythrityl tetranitrate
esatenolol
esmolol +
esmolol hydrochloride
Eunicea sesquiterpenoid 2
Eunicea sesquiterpenoid 3
everolimus
ezogabine
FD-211
felodipine
fenfluramine +
fenoldopam
fenoterol +
flavan-3,3',4',5,5',7-hexol +
flavan-3,3',4,4',5,5',7-heptol +
fleephilone
flupenthixol
fomitoside E
fosinopril
fosinopril sodium
fosinoprilat +
FR177391
FR901465
furanocandin
fuzanin D
germanicol
geumonoid
glafenine
glomosporin
glutinol
graminone B
grayanotoxin I
GTRI-02
guanadrel
guanadrel sulfate
guanethidine +
guanethidine monosulfate +
guanethidine sulfate
hookerianamide J
hydralazine +
hydralazine hydrochloride
hydrogen sulfide +
hyperinol A
hyperinol B
hyperxanthone C
icatibant +
icatibant acetate
idazoxan +
Ile(5)-angiotensin II (1-7)
iloprost
iminodiacetonitrile
indacaterol
indapamide
inflexin
integracin B
irbesartan
isoamyl nitrite
isomultiflorenol
isoprenaline
isopropyl unoprostone
isosecotanapartholide
isosorbide dinitrate
isosorbide mononitrate
ixerochinolide
jaspamide K
jaspamide N
juglanin B
kadlongilactone A
kaempferide
karakoline
ketamine +
ketanserin
kunzeaol
labetalol
latanoprost
latanoprost free acid +
lespeflorin C3
leucosesterterpenone
levobunolol +
levobunolol hydrochloride
levosimendan
lisinopril dihydrate
lofexidine
losartan
lucialdehyde C
lucidenic acid N
lupan-3beta,20-diol
lupeol +
magnesium sulfate +
metachromin S
methacholine +
methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate +
methyl 3-hydroxypiperidine-1-carboxylate
methyl 4-amino-2-(2,3-dihydroxy-3-methylbutyl)benzoate
methyl 4-hydroxypiperidine-2-carboxylate
methyl 4-hydroxypiperidine-3-carboxylate
methyl 5-hydroxypiperidine-2-carboxylate
metipranolol
metipranolol hydrochloride
metolazone
metoprolol
mianserin +
midodrine +
migrastatin
militarinone A
milrinone
minoxidil
mirtazapine
multiplolide A
multiplolide B
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride
N-[2-hydroxy-5-(1-hydroxy-2-\{[1-(4-methoxyphenyl)propan-2-yl]amino\}ethyl)phenyl]formamide +
N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-alaninamide
N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-cysteinamide
N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-serinamide
N-ethylasparagine +
N-methyl-1-(5-pyridin-3-ylfuran-2-yl)methanamine
N-methylglucamine +
n-pentyl nitrite
nadolol
nebivolol
nefazodone +
nicotinic acid +
nifedipine
nimodipine
nitric oxide
nitroglycerin
NK154183A
NK154183B
norajmaline +
norcaesalpinin E
olmesartan
p-aminodiphenylamine
palmitoyl ethanolamide
partial prostacyclin agonist +
penbutolol sulfate
pentaerythritol tetranitrate
pentolinium tartrate
perhexiline
PF 1163A
pimobendan
pindolol +
pleosporone
PM-94128
poly(vinylcarbazole) macromolecule +
practolol
pratosartan
pravastatin
prazosin +
prochlorperazine +
propafenone
propan-2-ol +
propranolol +
prostaglandin E1 +
pseudoephedrine +
quinidine +
rescinnamine
reserpine
reversine
risperidone
roxindole
sarpagine +
sch 54445
secondary amine +
sertindole
sertraline
sildenafil +
sildenafil citrate
sirolimus +
solavetivol
sophoradiol
sotalol
sotalol hydrochloride
sphingosine 1-phosphate
spiperone
spironolactone
strigol
sulcatol
tadalafil
tamsulosin +
tanespimycin
taraxasterol
taraxerol
telmisartan
terazosin +
tetrahydro-4-hydroxyphenylpyruvic acid
tetrahydrotyrosine
theobromine
theophylline +
thioridazine +
ticagrelor
TMC-135A
TMC-135B
TMC-1A
TMC-1B
TMC-1C
TMC-1D
TMC-52A
TMC-52B
TMC-52C
TMC-52D
TMC-86A
TMC-89A
TMC-89B
TMC-95A
TMC-95B
TMC-95C
TMC-95D
TMC-96
tolazoline
tolypodiol
trans-2-hydroxyisoxypropyl-3-hydroxy-7-isopentene-2,3-dihydrobenzofuran-5-carboxylic acid
travoprost
travoprost free acid +
treprostinil +
trierixin
trimethaphan +
troglitazone
tubelactomicin A
tubulosine
uniconazole
unoprostone +
valsartan
vardenafil
vasoconstrictor agent +
vasodilator agent +
veracevine
verapamil +
vincamine
ximelagatran
YM-47522
yohimbine
zomepirac
zuclopenthixol
|
|
|
|
|
