ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid metabolic pathway
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Accession:PW:0001004 term browser browse the term
Definition:The reactions involved in deriving retinoic acid (RA) from retinal and its further processing to more polar derivatives. Retinoic acid engages several retinoic acid receptors; its actions are important for the neuro and immune system functions and energy balance. Deregulation of proper RA activity has been associated with obesity and cancer.
Synonyms:exact_synonym: RA metabolic pathway
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retinoic acid metabolic pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 GBrowse link TAS 1 223,731,675 223,773,285 RGD:6484672 RGD
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 GBrowse link IMP 1 223,731,675 223,773,285 RGD:6771354 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link IEP 8 75,692,099 75,771,159 RGD:6771322 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link TAS 8 75,692,099 75,771,159 RGD:6484672 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link IMP 8 75,692,099 75,771,159 RGD:6771354 RGD
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 GBrowse link IEP 1 120,847,746 120,881,883 RGD:6771322 RGD
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 GBrowse link ISS 1 120,847,746 120,881,883 RGD:6484672 RGD
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 GBrowse link IMP 1 120,847,746 120,881,883 RGD:6771354 RGD
G Crabp1 cellular retinoic acid binding protein 1 GBrowse link ISS 8 58,317,337 58,325,375 RGD:6484672 RGD
G Crabp2 cellular retinoic acid binding protein 2 GBrowse link ISS 2 180,029,801 180,034,147 RGD:6484672 RGD
G Crabp2 cellular retinoic acid binding protein 2 GBrowse link IEP 2 180,029,801 180,034,147 RGD:6771322 RGD
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 GBrowse link ISS 1 241,945,472 241,949,220 RGD:6484672 RGD
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 GBrowse link IEP 1 241,945,472 241,949,220 RGD:6484694 RGD
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 GBrowse link ISS 4 118,734,786 118,751,606 RGD:6484672 RGD
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 GBrowse link IEP 4 118,734,786 118,751,606 RGD:6484694 RGD
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 GBrowse link IMP 4 118,734,786 118,751,606 RGD:6771354 RGD
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 GBrowse link ISS 1 241,954,251 241,961,689 RGD:6484672 RGD
G Dhrs9 dehydrogenase/reductase (SDR family) member 9 GBrowse link IEP 3 51,521,343 51,543,552 RGD:6771322 RGD
G Dhrs9 dehydrogenase/reductase (SDR family) member 9 GBrowse link ISS 3 51,521,343 51,543,552 RGD:6484672 RGD
G Dhrs9 dehydrogenase/reductase (SDR family) member 9 GBrowse link IMP 3 51,521,343 51,543,552 RGD:6771354 RGD
G Fabp5 fatty acid binding protein 5, epidermal ISS RGD:6484672 RGD
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) GBrowse link ISS 2 174,636,382 174,645,444 RGD:6484672 RGD
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) GBrowse link IEP 2 174,636,382 174,645,444 RGD:6484694 RGD
G Rbp1 retinol binding protein 1, cellular GBrowse link IEP 8 103,605,870 103,627,390 RGD:6771322 RGD
G Rbp1 retinol binding protein 1, cellular GBrowse link ISS 8 103,605,870 103,627,390 RGD:6484672 RGD
G Rbp4 retinol binding protein 4, plasma GBrowse link ISS 1 242,443,795 242,450,997 RGD:6484671 RGD
G Rbp4 retinol binding protein 4, plasma GBrowse link ISS 1 242,443,795 242,450,997 RGD:6484672 RGD
G Rdh10 retinol dehydrogenase 10 (all-trans) GBrowse link ISS 5 2,286,373 2,314,154 RGD:6484672 RGD
G Rdh10 retinol dehydrogenase 10 (all-trans) GBrowse link IMP 5 2,286,373 2,314,154 RGD:6771354 RGD
G Rdh16 retinol dehydrogenase 16 (all-trans) GBrowse link IMP 7 67,752,257 67,766,995 RGD:6771354 RGD
G Rdh7 retinol dehydrogenase 7 GBrowse link TAS 7 67,818,370 67,831,729 RGD:6484672 RGD
G Stra6 stimulated by retinoic acid 6 GBrowse link ISS 8 61,920,772 61,939,791 RGD:6484671 RGD
G Stra6 stimulated by retinoic acid 6 GBrowse link ISS 8 61,920,772 61,939,791 RGD:6484672 RGD
G Stra6 stimulated by retinoic acid 6 GBrowse link IEP 8 61,920,772 61,939,791 RGD:6484694 RGD
G Ttr transthyretin GBrowse link ISS 18 12,406,571 12,413,680 RGD:6484671 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  Pathway Ontology 17140
    classic metabolic pathway 3638
      metabolic pathway of cofactors and vitamins 437
        retinoid metabolic pathway 125
          retinoic acid metabolic pathway 35
Path 2
Term Annotations click to browse term
  Pathway Ontology 17140
    regulatory pathway 5692
      homeostasis pathway 2069
        vitamin homeostasis 205
          vitamin A homeostasis 205
            retinoid metabolic pathway 125
              retinoic acid metabolic pathway 35
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