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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:microRNA pathway
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Accession:PW:0000808 term browser browse the term
Definition:MicroRNAs (miRNAs) are a large family of small RNAs involved in the post-transcriptional regulation of gene expression. The biogenesis and function of miRNA is subject to complex control. Deregulation of miRNA expression has been linked to many diseases including cancer.
Synonyms:related_synonym: MicroRNA (miRNA) biogenesis;   miRNA pathway;   production of miRNAs involved in gene silencing by miRNA
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microRNA pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific ISO RGD PMID:22001383 RGD:9850105 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 ISO RGD PMID:22001383 RGD:9850105 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Ago1 argonaute RISC component 1 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
G Ago4 argonaute RISC component 4 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 5:138,780,446...138,825,898
Ensembl chr 5:138,783,069...138,825,632 		JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 ISO RGD PMID:23337855 RGD:9850101 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574 		JBrowse link
G Cnot10 CCR4-NOT transcription complex, subunit 10 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 8:114,280,486...114,330,110
Ensembl chr 8:114,280,490...114,330,107 		JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 7:52,130,445...52,222,338
Ensembl chr 7:52,130,441...52,223,575 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 ISO RGD PMID:23337855 RGD:9850101 NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025 		JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like ISO RGD PMID:23337855 RGD:9850101 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 ISO RGD PMID:23337855 RGD:9850101 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Cnot8 CCR4-NOT transcription complex, subunit 8 ISO RGD PMID:23337855 RGD:9850101 NCBI chr10:42,281,614...42,294,740
Ensembl chr10:42,281,722...42,294,730 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100 		JBrowse link
G Dcp1b decapping mRNA 1B ISO RGD PMID:24352420 RGD:9850104 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145 		JBrowse link
G Dcp2 decapping mRNA 2 ISO RGD PMID:24352420 RGD:9850104 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Ddx6 DEAD-box helicase 6 ISO RGD PMID:24352420 RGD:9850104 NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit ISO RGD PMID:20661255 RGD:4144851 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO RGD PMID:20661255 RGD:4144851 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Drosha drosha ribonuclease III ISO RGD PMID:20661255 RGD:4144851 NCBI chr 2:61,864,886...61,976,688
Ensembl chr 2:61,864,970...61,976,688 		JBrowse link
G Edc3 enhancer of mRNA decapping 3 ISO RGD PMID:24352420 RGD:9850104 NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671 		JBrowse link
G Edc4 enhancer of mRNA decapping 4 ISO RGD PMID:24352420 RGD:9850104 NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744 		JBrowse link
G Pan2 poly(A) specific ribonuclease subunit PAN2 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 7:729,146...747,744
Ensembl chr 7:729,562...747,744 		JBrowse link
G Pan3 poly(A) specific ribonuclease subunit PAN3 ISO RGD PMID:23337855 RGD:9850101 NCBI chr12:7,476,707...7,595,384
Ensembl chr12:7,476,697...7,599,204 		JBrowse link
G Patl1 PAT1 homolog 1, processing body mRNA decay factor ISO RGD PMID:24352420 RGD:9850104 NCBI chr 1:208,831,115...208,862,904
Ensembl chr 1:208,831,115...208,862,857 		JBrowse link
G Ran RAN, member RAS oncogene family ISO RGD PMID:19965479 RGD:4144860 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex ISO RGD PMID:20661255 RGD:4144851 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A ISO RGD PMID:20484662 RGD:4144862 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660 		JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B ISO RGD PMID:20484662 RGD:4144862 NCBI chr 7:112,252,351...112,469,829
Ensembl chr 7:112,252,359...112,461,790 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C ISO RGD PMID:20484662 RGD:4144862 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194 		JBrowse link
G Tut4 terminal uridylyl transferase 4 ISO RGD PMID:23622238 RGD:9850106 NCBI chr 5:123,201,723...123,306,582
Ensembl chr 5:123,203,003...123,306,465 		JBrowse link
G Tut7 terminal uridylyl transferase 7 ISO RGD PMID:23622238 RGD:9850106 NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169 		JBrowse link
G Xpo5 exportin 5 ISO RGD PMID:19965479 RGD:4144860 NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1752
        non-coding RNA pathway 35
          small non-coding RNA pathway 35
            microRNA pathway 35
              altered microRNA pathway 0
paths to the root