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Term: insulin responsive facilitative sugar transporter mediated glucose transport pathway
Accession: PW:0000639
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Definition: The GLUT family contains 14 members in mammals which can be grouped into 3 classes based on sequence similarities. The members of group I (best characterized) and of group III transporters facilitate glucose transport. Of the three members of group I, Slc2a4 (Glut4), is involved in insulin-mediated uptake of glucose in the heart, skeletal muscle and adipose tissue. The response - central to glucose homeostasis - brings together several signaling and trafficking events.
Synonyms: related_synonym: PID:200196
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insulin responsive facilitative sugar transporter mediated glucose transport pathway
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
IMP
6
137,640,482
137,657,552
RGD:2306432
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
ISO
6
137,640,482
137,657,552
RGD:6484113
PID
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
ISS
1
82,686,233
82,726,544
RGD:2302395
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
IMP
1
82,686,233
82,726,544
RGD:2306432
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
ISS
1
82,686,233
82,726,544
RGD:2302397
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
ISO
1
82,686,233
82,726,544
RGD:6484113
PID
G
Asip
agouti signaling protein
ISO
3
145,445,175
145,536,831
RGD:6484113
PID
G
Calm1
calmodulin 1
ISO
6
124,477,601
124,485,669
RGD:6484113
PID
G
Calm2
calmodulin 2
ISO
6
64,161,641
64,162,751
RGD:6484113
PID
G
Calm3
calmodulin 3
ISO
1
77,245,609
77,252,717
RGD:6484113
PID
G
Gsk3b
glycogen synthase kinase 3 beta
ISO
11
64,284,731
64,428,698
RGD:6484113
PID
G
Gys1
glycogen synthase 1, muscle
ISO
1
95,907,458
95,928,150
RGD:6484113
PID
G
Ins2
insulin 2
ISO
1
202,935,548
202,936,379
RGD:6484113
PID
G
Insr
insulin receptor
ISO
12
2,934,967
3,087,691
RGD:6484113
PID
G
Lnpep
leucyl/cystinyl aminopeptidase
ISS
1
56,063,361
56,151,257
RGD:2302393
RGD
G
Lnpep
leucyl/cystinyl aminopeptidase
IMP
1
56,063,361
56,151,257
RGD:2306436
RGD
G
Lnpep
leucyl/cystinyl aminopeptidase
ISO
1
56,063,361
56,151,257
RGD:6484113
PID
G
Myo5a
myosin VA
ISS
8
79,909,224
80,027,290
RGD:2302397
RGD
G
Ppp1cc
protein phosphatase 1, catalytic subunit, gamma isozyme
ISO
12
35,580,169
35,598,249
RGD:6484113
PID
G
Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
ISO
4
40,195,325
40,235,913
RGD:6484113
PID
G
Prkci
protein kinase C, iota
ISO
2
116,739,625
116,801,084
RGD:6484113
PID
G
Prkcz
protein kinase C, zeta
ISO
5
172,061,825
172,172,793
RGD:6484113
PID
G
Rab10
RAB10, member RAS oncogene family
ISS
RGD:2302397
RGD
G
Rab10
RAB10, member RAS oncogene family
ISS
RGD:2302395
RGD
G
Rab10
RAB10, member RAS oncogene family
ISS
RGD:2302393
RGD
G
Rab11a
RAB11a, member RAS oncogene family
ISS
8
68,931,925
68,979,514
RGD:2302395
RGD
G
Rab11a
RAB11a, member RAS oncogene family
ISS
8
68,931,925
68,979,514
RGD:2302397
RGD
G
Rab14
RAB14, member RAS oncogene family
ISS
3
14,245,693
14,255,984
RGD:2302393
RGD
G
Rab14
RAB14, member RAS oncogene family
ISS
3
14,245,693
14,255,984
RGD:2302395
RGD
G
Rab14
RAB14, member RAS oncogene family
ISS
3
14,245,693
14,255,984
RGD:2302397
RGD
G
Rab14
RAB14, member RAS oncogene family
IMP
3
14,245,693
14,255,984
RGD:2306295
RGD
G
Rab2a
RAB2A, member RAS oncogene family
ISS
5
22,389,585
22,452,198
RGD:2302393
RGD
G
Rab2a
RAB2A, member RAS oncogene family
ISS
5
22,389,585
22,452,198
RGD:2302395
RGD
G
Rab2a
RAB2A, member RAS oncogene family
ISS
5
22,389,585
22,452,198
RGD:2302397
RGD
G
Rab4a
RAB4A, member RAS oncogene family
IMP
19
53,991,122
54,019,248
RGD:2306268
RGD
G
Rab4a
RAB4A, member RAS oncogene family
ISS
19
53,991,122
54,019,248
RGD:2302397
RGD
G
Rab4a
RAB4A, member RAS oncogene family
ISS
19
53,991,122
54,019,248
RGD:2302395
RGD
G
Rab5a
RAB5A, member RAS oncogene family
ISS
9
1,492,864
1,516,405
RGD:2302395
RGD
G
Rab8a
RAB8A, member RAS oncogene family
ISS
16
18,078,519
18,099,882
RGD:2302393
RGD
G
Rab8a
RAB8A, member RAS oncogene family
ISS
16
18,078,519
18,099,882
RGD:2302395
RGD
G
Rab8a
RAB8A, member RAS oncogene family
IMP
16
18,078,519
18,099,882
RGD:2306295
RGD
G
Rab8a
RAB8A, member RAS oncogene family
ISS
16
18,078,519
18,099,882
RGD:2302397
RGD
G
Rab8b
RAB8B, member RAS oncogene family
ISS
8
71,156,502
71,231,807
RGD:2302397
RGD
G
Rhoq
ras homolog family member Q
ISO
6
10,414,042
10,449,472
RGD:6484113
PID
G
Sfn
stratifin
ISO
5
151,475,395
151,479,996
RGD:6484113
PID
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
ISS
10
56,786,705
56,792,209
RGD:2302397
RGD
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
ISS
10
56,786,705
56,792,209
RGD:2302395
RGD
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
IMP
10
56,786,705
56,792,209
RGD:2306268
RGD
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
IDA
10
56,786,705
56,792,209
RGD:2303167
RGD
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
ISS
10
56,786,705
56,792,209
RGD:2302393
RGD
G
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
ISO
10
56,786,705
56,792,209
RGD:6484113
PID
G
Snap23
synaptosomal-associated protein 23
ISS
3
107,361,066
107,362,878
RGD:2302397
RGD
G
Snap23
synaptosomal-associated protein 23
ISS
3
107,361,066
107,362,878
RGD:2302393
RGD
G
Stx4
syntaxin 4
ISS
1
187,125,847
187,132,932
RGD:2302393
RGD
G
Stx4
syntaxin 4
ISS
1
187,125,847
187,132,932
RGD:2302397
RGD
G
Stx4
syntaxin 4
ISO
1
187,125,847
187,132,932
RGD:6484113
PID
G
Stxbp3
syntaxin binding protein 3
ISS
2
204,395,554
204,439,388
RGD:2302393
RGD
G
Stxbp3
syntaxin binding protein 3
ISS
2
204,395,554
204,439,388
RGD:2302397
RGD
G
Stxbp4
syntaxin binding protein 4
ISS
10
78,887,817
79,039,618
RGD:2302395
RGD
G
Stxbp4
syntaxin binding protein 4
ISO
10
78,887,817
79,039,618
RGD:6484113
PID
G
Trip10
thyroid hormone receptor interactor 10
ISO
RGD:6484113
PID
G
Vamp2
vesicle-associated membrane protein 2
ISS
10
55,848,264
55,852,132
RGD:2302397
RGD
G
Vamp2
vesicle-associated membrane protein 2
ISS
10
55,848,264
55,852,132
RGD:2302393
RGD
G
Vamp2
vesicle-associated membrane protein 2
ISO
10
55,848,264
55,852,132
RGD:6484113
PID
G
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ISO
3
154,926,025
154,948,297
RGD:6484113
PID
G
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
ISO
10
63,072,128
63,109,833
RGD:6484113
PID
G
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
ISO
12
21,859,804
21,888,050
RGD:6484113
PID
G
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
ISO
14
83,448,395
83,457,778
RGD:6484113
PID
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
ISO
6
41,945,769
41,976,123
RGD:6484113
PID
G
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
ISO
7
72,283,825
72,306,126
RGD:6484113
PID
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